Curated repository for small angle scattering data and models


SASBDB currently contains:


3809

experimental data sets

5273

models
493 experimental data sets on hold
401 models on hold

Small angle scattering (SAS) of X-ray and neutrons provides structural information on biological macromolecules in solution at a resolution of 1-2 nm.
SASBDB is a fully searchable curated repository of freely accessible and downloadable experimental data, which are deposited together with the relevant experimental conditions, sample details, derived models and their fits to the data.

Recent depositions:

SASDPQ5 – His-tagged L-methionine gamma-lyase from Clostridium tetani

L-methionine gamma-lyase experimental SAS data
CHIMERA model
Sample: L-methionine gamma-lyase tetramer, 181 kDa Clostridium tetani protein
Buffer: PBS-D2O: 137 mM NaCl, 2.7 mM KCl, 10 mM Na2HPO4, 1.8 mM KH2PO4 (D2O buffer), pH: 7.4
Experiment: SANS data collected at YuMO SANS TOF spectrometer, IBR-2, Frank Laboratory of Neutron Physics, Joint Institute for Nuclear Research on 2019 May 19
Methionine gamma lyase fused with S3 domain VGF forms octamers and adheres to tumor cells via binding EGFR Biochemical and Biophysical Research Communications :149319 (2023)
Bondarev N, Bagaeva D, Bazhenov S, Buben M, Bulushova N, Ryzhykau Y, Okhrimenko I, Zagryadskaya Y, Maslov I, Anisimova N, Sokolova D, Kuklin A, Pokrovsky V, Manukhov I
RgGuinier 4.0 nm
Dmax 14.9 nm
VolumePorod 232 nm3

Ribosome maturation factor RimP bound to 30S ribosomal protein S12 (RimP-uS12 complex from Staphylococcus aureus)
Ribosome maturation factor RimP30S ribosomal protein S12 experimental SAS data
Structural aspects of RimP binding on small ribosomal subunit from Staphylococcus aureus. Structure 2023 Nov 14;
Structure (2023 Nov 14)
His-Tagged Monomeric DNA repair protein RAD51 homolog 1 double mutant [F86E, A89E] in complex with His-tagged fourth BRC repeat (BRC4)
DNA repair protein RAD51 homolog 1 (F86E, A89E, His-Tagged)Breast cancer type 2 susceptibility protein experimental SAS data
Isolation and characterization of monomeric human RAD51: a novel tool for investigating homologous recombination in cancer Angewandte Chemie International Edition 2023 Nov 04
Angewandte Chemie International Edition (2023 Nov 04)
Interleukin 11 signalling complex, full-length extracellular gp130
Interleukin-11Interleukin-11 receptor subunit alphaInterleukin-6 receptor subunit beta experimental SAS data
Structures of the interleukin 11 signalling complex reveal gp130 dynamics and the inhibitory mechanism of a cytokine variant Nature Communications 2023 Nov 20 14(1)
Nature Communications 14(1) (2023 Nov 20)
Full length human mature gelsolin in closed state
Gelsolin experimental SAS data
Accurate and Efficient SAXS/SANS Implementation Including Solvation Layer Effects Suitable for Molecular Simulations. J Chem Theory Comput 2023 Nov 3;
J Chem Theory Comput (2023 Nov 3)
Mouse guanylate-binding protein 7 - mGBP7
Gbp6 protein (Gbp7 - Gbp6 protein Mus musculus) experimental SAS data
Integrative modeling of guanylate binding protein dimers Protein Science 2023 Nov 02
Protein Science (2023 Nov 02)

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To cite SASBDB refer to: Kikhney AG, Borges CR, Molodenskiy DS, Jeffries CM, Svergun DI (2020) SASBDB: Towards an automatically curated and validated repository for biological scattering data. Protein Science 29(1); 66-75.