Curated repository for small angle scattering data and models


SASBDB currently contains:


939

experimental data sets

1418

models
229 experimental data sets on hold
311 models on hold

Small angle scattering (SAS) of X-ray and neutrons provides structural information on biological macromolecules in solution at a resolution of 1-2 nm.
SASBDB is a fully searchable curated repository of freely accessible and downloadable experimental data, which are deposited together with the relevant experimental conditions, sample details, derived models and their fits to the data.

Recent depositions:

SASDEK3 – The neutrophil cytosol factor 1 (p47phox) subunit of phagocyte NADPH oxidase

Neutrophil cytosol factor 1 experimental SAS data
CUSTOM IN-HOUSE model
Sample: Neutrophil cytosol factor 1 monomer, 46 kDa Homo sapiens protein
Buffer: 50 mM HEPES, 100 mM NaCl, 1 mM EDTA, 2 mM DTT, 5% glycerol, pH: 7.5
Experiment: SAXS data collected at SWING, SOLEIL on 2008 Apr 23
Quantitative live-cell imaging and 3D modeling reveal critical functional features in the cytosolic complex of phagocyte NADPH oxidase. J Biol Chem (2019)
Ziegler CS, Bouchab L, Tramier M, Durand D, Fieschi F, Dupré-Crochet S, Mérola F, Nüße O, Erard M
RgGuinier 3.2 nm
Dmax 12.5 nm
VolumePorod 77 nm3

SASDE24 – Tryparedoxin, in the presence of inhibitor CFT (2-(chloromethyl)-5-(4-fluorophenyl)thieno[2,3-d]pyrimidin-4(3H)-one)
Tryparedoxin experimental SAS data
SASREF MX model
Inhibitor-induced dimerization of an essential oxidoreductase from African Trypanosomes.
SASDDJ6 – SAM-dependent O-Methyltransferase from Mycobacterium hassiacum
Methyltransferase domain protein experimental SAS data
MODELLER model
Biosynthesis of mycobacterial methylmannose polysaccharides requires a unique 1-O-methyltransferase specific for 3-O-methylated mannosides
SASDE96 – Aldehyde dehydrogenase 12 from Zea mays Extrapolated to Infinite Dilution
Aldehyde dehydrogenase 12 experimental SAS data
ALLOSMOD model
Structural and Biochemical Characterization of Aldehyde Dehydrogenase 12, the Last Enzyme of Proline Catabolism in Plants.
SASDEE2 – The N-terminal domain of estrogen receptor alpha
The N-terminal domain of estrogen receptor alpha experimental SAS data
CUSTOM IN-HOUSE model
A Metastable Contact and Structural Disorder in the Estrogen Receptor Transactivation Domain
SASDE27 – Gamma-crystallin S monomer
Gamma-crystallin S experimental SAS data
CHIMERA model
The structure and stability of the disulfide-linked γS-crystallin dimer provide insight into oxidation products associated with lens cataract formation.

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