Browse by MODEL: Hybrid

SASDVN5 – NT17 peptide

NT17 experimental SAS data
ROSETTA model
Sample: NT17 monomer, 2 kDa synthetic construct protein
Buffer: Sodium phosphate buffer, pH: 7.4
Experiment: SAXS data collected at TPS13A, NSRRC on 2021 Oct 21
Binding structures of SERF1a with NT17-polyQ peptides of huntingtin exon 1 revealed by SEC-SWAXS, NMR and molecular simulation. IUCrJ (2024)
Lin TC, Shih O, Tsai TY, Yeh YQ, Liao KF, Mansel BW, Shiu YJ, Chang CF, Su AC, Chen YR, Jeng US
RgGuinier 1.2 nm
Dmax 4.0 nm
VolumePorod 5 nm3

SASDVP5 – HTT0 peptide

HTT0 experimental SAS data
ROSETTA model
Sample: HTT0 monomer, 4 kDa synthetic construct protein
Buffer: Sodium phosphate buffer, pH: 7.4
Experiment: SAXS data collected at TPS13A, NSRRC on 2023 Nov 10
Binding structures of SERF1a with NT17-polyQ peptides of huntingtin exon 1 revealed by SEC-SWAXS, NMR and molecular simulation. IUCrJ (2024)
Lin TC, Shih O, Tsai TY, Yeh YQ, Liao KF, Mansel BW, Shiu YJ, Chang CF, Su AC, Chen YR, Jeng US
RgGuinier 1.5 nm
Dmax 6.0 nm
VolumePorod 4 nm3

SASDVR5 – Small EDRK-rich factor 1 (SERF1a) bound to NT17 peptide

Isoform Short of Small EDRK-rich factor 1NT17 experimental SAS data
ROSETTA model
Sample: Isoform Short of Small EDRK-rich factor 1 monomer, 7 kDa Homo sapiens protein
NT17 dimer, 4 kDa synthetic construct protein
Buffer: Sodium phosphate buffer, pH: 7.4
Experiment: SAXS data collected at TPS13A, NSRRC on 2021 Oct 21
Binding structures of SERF1a with NT17-polyQ peptides of huntingtin exon 1 revealed by SEC-SWAXS, NMR and molecular simulation. IUCrJ (2024)
Lin TC, Shih O, Tsai TY, Yeh YQ, Liao KF, Mansel BW, Shiu YJ, Chang CF, Su AC, Chen YR, Jeng US
RgGuinier 2.3 nm

SASDVS5 – Small EDRK-rich factor 1 (SERF1a) bound to HTT-3 peptide

Isoform Short of Small EDRK-rich factor 1HTT3 experimental SAS data
ROSETTA model
Sample: Isoform Short of Small EDRK-rich factor 1 monomer, 7 kDa Homo sapiens protein
HTT3 monomer, 4 kDa synthetic construct protein
Buffer: Sodium phosphate buffer, pH: 7.4
Experiment: SAXS data collected at TPS13A, NSRRC on 2021 May 20
Binding structures of SERF1a with NT17-polyQ peptides of huntingtin exon 1 revealed by SEC-SWAXS, NMR and molecular simulation. IUCrJ (2024)
Lin TC, Shih O, Tsai TY, Yeh YQ, Liao KF, Mansel BW, Shiu YJ, Chang CF, Su AC, Chen YR, Jeng US
RgGuinier 2.3 nm
Dmax 7.2 nm
VolumePorod 9 nm3

SASDRY9 – Regulator of telomere elongation helicase 1, HHD-2 domain

Regulator of telomere elongation helicase 1 (Isoform 6, 1053-1147) experimental SAS data
ALPHAFOLD model
Sample: Regulator of telomere elongation helicase 1 (Isoform 6, 1053-1147) monomer, 11 kDa Homo sapiens protein
Buffer: 50 mM Hepes, 150 mM NaCl,10 (v/v)% glycerol, 1 mM TCEP, pH: 7
Experiment: SAXS data collected at EMBL P12, PETRA III on 2022 Mar 22
Structural and biochemical characterization of the C‐terminal region of the human RTEL 1 helicase Protein Science 33(9) (2024)
Cortone G, Graewert M, Kanade M, Longo A, Hegde R, González‐Magaña A, Chaves‐Arquero B, Blanco F, Napolitano L, Onesti S
RgGuinier 1.5 nm
Dmax 5.0 nm
VolumePorod 24 nm3

SASDRZ9 – Regulator of telomere elongation helicase 1, HHD-1 domain

Regulator of telomere elongation helicase 1 (Isoform 6, 889-974) experimental SAS data
ALPHAFOLD model
Sample: Regulator of telomere elongation helicase 1 (Isoform 6, 889-974) monomer, 10 kDa Homo sapiens protein
Buffer: 50 mM Tris, 150 mM NaCl,10 (v/v)% glycerol, 1 mM TCEP, pH: 8
Experiment: SAXS data collected at EMBL P12, PETRA III on 2022 Mar 22
Structural and biochemical characterization of the C‐terminal region of the human RTEL 1 helicase Protein Science 33(9) (2024)
Cortone G, Graewert M, Kanade M, Longo A, Hegde R, González‐Magaña A, Chaves‐Arquero B, Blanco F, Napolitano L, Onesti S
RgGuinier 1.5 nm
Dmax 4.6 nm
VolumePorod 22 nm3

SASDTQ5 – SemDΔAPH (apo form)

Uncharacterized protein experimental SAS data
CORAL model
Sample: Uncharacterized protein monomer, 35 kDa Chlamydia pneumoniae protein
Buffer: 137 mM NaCl, 2.7 mM KCl, 10 mM Na2HPO4, 1.8 mM KH2PO4, 3 %Glycerol, pH: 8.5
Experiment: SAXS data collected at EMBL P12, PETRA III on 2022 Dec 14
The Chlamydia pneumoniae effector SemD exploits its host’s endocytic machinery by structural and functional mimicry Nature Communications 15(1) (2024)
Kocher F, Applegate V, Reiners J, Port A, Spona D, Hänsch S, Mirzaiebadizi A, Ahmadian M, Smits S, Hegemann J, Mölleken K
RgGuinier 2.8 nm
Dmax 10.5 nm
VolumePorod 67 nm3

SASDTT5 – SemDΔAPH bound to Sorting nexin-9, N-terminus - SNX9-SH3

Uncharacterized proteinSorting nexin-9 experimental SAS data
CORAL model
Sample: Uncharacterized protein monomer, 35 kDa Chlamydia pneumoniae protein
Sorting nexin-9 monomer, 19 kDa Homo sapiens protein
Buffer: 137 mM NaCl, 2.7 mM KCl, 10 mM Na2HPO4, 1.8 mM KH2PO4, 3 %Glycerol, pH: 8.5
Experiment: SAXS data collected at EMBL P12, PETRA III on 2023 Mar 20
The Chlamydia pneumoniae effector SemD exploits its host’s endocytic machinery by structural and functional mimicry Nature Communications 15(1) (2024)
Kocher F, Applegate V, Reiners J, Port A, Spona D, Hänsch S, Mirzaiebadizi A, Ahmadian M, Smits S, Hegemann J, Mölleken K
RgGuinier 3.4 nm
Dmax 12.2 nm
VolumePorod 94 nm3

SASDQA7 – Homodimeric luciferase EsLuxA

Alkanal monooxygenase alpha chain experimental SAS data
ALPHAFOLD model
Sample: Alkanal monooxygenase alpha chain dimer, 84 kDa Enhygromyxa salina protein
Buffer: 150 mM NaCl, 25 mM Tris, pH: 8
Experiment: SAXS data collected at Rigaku MicroMax 007-HF, Moscow Institute of Physics and Technology (MIPT) on 2020 Aug 1
luxA Gene From Enhygromyxa salina Encodes a Functional Homodimeric Luciferase Proteins: Structure, Function, and Bioinformatics (2024)
Yudenko A, Bazhenov S, Aleksenko V, Goncharov I, Semenov O, Remeeva A, Nazarenko V, Kuznetsova E, Fomin V, Konopleva M, Al Ebrahim R, Sluchanko N, Ryzhykau Y, Semenov Y, Kuklin A, Manukhov I, Gushchin I
RgGuinier 3.3 nm
Dmax 12.5 nm
VolumePorod 138 nm3

SASDUW3 – Calcium activated full-length gelsolin

Gelsolin experimental SAS data
PYMOL model
Sample: Gelsolin monomer, 84 kDa Homo sapiens protein
Buffer: 25 mM Tris-HCl, pH8, 45 mM NaCl, 1 mM EGTA + 4 mM CaCl2, pH: 8
Experiment: SAXS data collected at EMBL P12, PETRA III on 2013 Aug 31
Visualizing the nucleating and capped states of f-actin by Ca(2+)-gelsolin: Saxs data based structures of binary and ternary complexes. Int J Biol Macromol :134556 (2024)
Sagar A, Peddada N, Choudhary V, Mir Y, Garg R, Ashish
RgGuinier 4.2 nm
Dmax 16.0 nm
VolumePorod 129 nm3