The herpes viral transcription factor ICP4 forms a novel DNA recognition complex.

Tunnicliffe RB, Lockhart-Cairns MP, Levy C, Mould AP, Jowitt TA, Sito H, Baldock C, Sandri-Goldin RM, Golovanov AP
Nucleic Acids Res 45(13):8064-8078 (2017 Jul 27)
PMID: 28505309
doi: 10.1093/nar/gkx419
Submitted to SASBDB: 2016 Nov 28
Published in SASBDB:

SASDB68 – Immediate Early 3 DNA (ICP4N IE3_19mer)

Immediate Early 3 experimental SAS data
Immediate Early 3 Kratky plot
Sample: Immediate Early 3 dimer, 12 kDa DNA
Buffer: 20 mM HEPES, 150 mM NaCl, pH: 7.4
Experiment: SAXS data collected at BM29, ESRF on 2015 Nov 12
RgGuinier 1.9 nm
Dmax 6.9 nm

SASDB58 – Major viral transcription factor ICP4 (ICP4N dimer)

Major viral transcription factor ICP4 experimental SAS data
Major viral transcription factor ICP4 Kratky plot
Sample: Major viral transcription factor ICP4 dimer, 49 kDa Human herpesvirus 1 … protein
Buffer: 20 mM HEPES, 150 mM NaCl, pH: 7.4
Experiment: SAXS data collected at B21, Diamond Light Source on 2015 Jul 27
RgGuinier 2.9 nm
Dmax 12.7 nm

SASDB48 – Major viral transcription factor ICP4/Immediate Early 3 DNA (ICP4N IE3_19mer) complex

Major viral transcription factor ICP4Immediate Early 3 experimental SAS data
NONE model
Sample: Major viral transcription factor ICP4 dimer, 49 kDa Human herpesvirus 1 … protein
Immediate Early 3 dimer, 12 kDa DNA
Buffer: 20 mM HEPES, 150 mM NaCl, pH: 7.4
Experiment: SAXS data collected at B21, Diamond Light Source on 2015 Jul 27
RgGuinier 2.5 nm
Dmax 8.3 nm
VolumePorod 90 nm3