A β(H)-spectrin self-interaction domain forms antiparallel dimers that may facilitate non-canonical spectrin membrane skeleton assembly.

Sarring C, Stoute JV, Armache JP, Yennawar NH, Thomas CM
J Biol Chem :113388 (2026 Aug 4)
PMID: 42551825
doi: 10.1016/j.jbc.2026.113388 		Submitted to SASBDB: 2026 Jun 18
Published in SASBDB:

SASD2D2 – Beta-Heavy-Spectrin fragment containing segments 25 to 31

Beta-Heavy-Spectrin experimental SAS data
CORAL model
Sample: Beta-Heavy-Spectrin dimer, 173 kDa Drosophila melanogaster protein
Buffer: 10 mM NaH2PO4, 130 mM NaCl, pH: 7.4
Experiment: SAXS data collected at Rigaku BioSAXS-2000, Pennsylvania State University on 2024 May 23
RgGuinier 7.8 nm
Dmax 35.8 nm
VolumePorod 453 nm3