The PHD and chromo domains regulate the ATPase activity of the human chromatin remodeler CHD4.

Watson AA, Mahajan P, Mertens HD, Deery MJ, Zhang W, Pham P, Du X, Bartke T, Zhang W, Edlich C, Berridge G, Chen Y, Burgess-Brown NA, Kouzarides T, Wiechens N, Owen-Hughes T, Svergun DI, Gileadi O, Laue ED
J Mol Biol 422(1):3-17 (2012 Sep 7)
PMID: 22575888
doi: 10.1016/j.jmb.2012.04.031
Published in SASBDB:

SASDA85 – CHD4 (PP-CC-AH-D)

Human Chromatin Remodeler CHD4 (363-1353) experimental SAS data
DAMMIF model
Sample: Human Chromatin Remodeler CHD4 (363-1353) monomer, 117 kDa Homo sapiens protein
Buffer: 50 mM HEPES 5% Glycerol 300 mM NaCl, pH: 7.5
Experiment: SAXS data collected at EMBL X33, DORIS III on 2010 Nov 13
RgGuinier 4.9 nm
Dmax 17.4 nm

SASDA95 – CHD4 (CC-AH-D)

Human Chromatin Remodeler CHD4 (494-1353) experimental SAS data
DAMMIF model
Sample: Human Chromatin Remodeler CHD4 (494-1353) monomer, 101 kDa Homo sapiens protein
Buffer: 50 mM HEPES 50 mM KCl, pH: 7.5
Experiment: SAXS data collected at EMBL X33, DORIS III on 2010 Nov 13
RgGuinier 4.0 nm
Dmax 14.5 nm

SASDAA5 – CHD4 (AH)

Human Chromatin Remodeler CHD4 (685-1233) experimental SAS data
DAMMIF model
Sample: Human Chromatin Remodeler CHD4 (685-1233) monomer, 63 kDa Homo sapiens protein
Buffer: 50 mM HEPES 50 mM KCl, pH: 7.5
Experiment: SAXS data collected at EMBL X33, DORIS III on 2010 Nov 13
RgGuinier 4.0 nm
Dmax 14.5 nm

SASDAB5 – CHD4 (PP-CC)

Human Chromatin Remodeler CHD4 (363-682) experimental SAS data
DAMMIF model
Sample: Human Chromatin Remodeler CHD4 (363-682) monomer, 38 kDa Homo sapiens protein
Buffer: 50 mM HEPES 50 mM KCl, pH: 7.5
Experiment: SAXS data collected at EMBL X33, DORIS III on 2010 Nov 13
RgGuinier 3.0 nm
Dmax 10.5 nm