An NAD+ Phosphorylase Toxin Triggers Mycobacterium tuberculosis Cell Death.

Freire DM, Gutierrez C, Garza-Garcia A, Grabowska AD, Sala AJ, Ariyachaokun K, Panikova T, Beckham KSH, Colom A, Pogenberg V, Cianci M, Tuukkanen A, Boudehen YM, Peixoto A, Botella L, Svergun DI, Schnappinger D, Schneider TR, Genevaux P, de Carvalho LPS, Wilmanns M, Parret AHA, Neyrolles O
Mol Cell (2019 Feb 8)
PMID: 30792174
doi: 10.1016/j.molcel.2019.01.028
Submitted to SASBDB: 2018 Jan 12
Published in SASBDB:

SASDD33 – Toxin/Antitoxin complex from M. tuberculosis

Mycobacterial cidal toxinMycobacterial cidal antitoxin experimental SAS data
PDB model
Sample: Mycobacterial cidal toxin hexamer, 121 kDa Mycobacterium tuberculosis (strain ... protein
Mycobacterial cidal antitoxin hexamer, 76 kDa Mycobacterium tuberculosis (strain ... protein
Buffer: 100 mM HEPES, 100 mM NaCl, pH: 7.5
Experiment: SAXS data collected at EMBL P12, PETRA III on 2015 Jun 2
RgGuinier 4.1 nm
Dmax 11.4 nm
VolumePorod 262 nm3