{"code":"SASDAU4","status":"Published","type_of_curve":"Merged","angular_unit":"1/nm","project":{"title":"A flexible multidomain structure drives the function of the urokinase-type plasminogen activator receptor (uPAR).","publication":{"title":"A flexible multidomain structure drives the function of the urokinase-type plasminogen activator receptor (uPAR).","author_list":"Mertens HD, Kjaergaard M, Mysling S, Gårdsvoll H, Jørgensen TJ, Svergun DI, Ploug M","journal":"J Biol Chem","doi":"10.1074/jbc.M112.398404","pmid":"22896701","published_date":"2012 Oct 5"},"status":"released","submitted_date":null,"released_date":"2015-07-07"},"pddf_data":"https://www.sasbdb.org/media/p_of_R_files/SASDAU4.out","intensities_data":"https://www.sasbdb.org/media/intensities_files/SASDAU4.dat","intensities_log_plot":"https://www.sasbdb.org/media/intensities_files/scattering_plots/SASDAU4_dat_img.png","intensities_kratky_plot":"https://www.sasbdb.org/media/intensities_files/scattering_plots/SASDAU4_kratky_img.png","pddf_plot":"https://www.sasbdb.org/media/p_of_R_files/pofr_images/SASDAU4_pofr_img.png","intensities_guinier_plot":"https://www.sasbdb.org/media/intensities_files/scattering_plots/SASDAU4_guinier_img.png","sascif_data":"https://www.sasbdb.org/media/sascif/sascif_files/SASDAU4.sascif","experiment":{"instrument":{"detector":{"type":"Custom-built","name":"Pilatus 1M-W","resolution":0.172},"name":"DORIS III, DESY","city":"Hamburg","country":"Germany","beamline_name":"EMBL X33","beam_geometry":"0.60","type_of_source":"X-ray synchrotron","point_source":null,"line_collimation":null,"sample_path_length":null,"line_collimation_slitlength":null,"line_collimation_integrationwidth":null,"xray_energy":null,"beam_profile_ah":null,"beam_profile_al":null},"sample":{"molecule":[{"long_name":"Urokinase plasminogen activator surface receptor","short_name":"uPAR","sequence":">sp|Q03405|UPAR_HUMAN Urokinase plasminogen activator surface receptor OS=Homo sapiens GN=PLAUR PE=1 SV=1\nMGHPPLLPLLLLLHTCVPASWGLRCMQCKTNGDCRVEECALGQDLCRTTIVRLWEEGEEL\nELVEKSCTHSEKTNRTLSYRTGLKITSLTEVVCGLDLCNQGNSGRAVTYSRSRYLECISC\nGSSDMSCERGRHQSLQCRSPEEQCLDVVTHWIQEGEEGRPKDDRHLRGCGYLPGCPGSNG\nFHNNDTFHFLKCCNTTKCNEGPILELENLPQNGRQCYSCKGNSTHGCSSEETFLIDCRGP\nMNQCLVATGTHEPKNQSYMVRGCATASMCQHAHLGDAFSMNHIDVSCCTKSGCNHPDLDV\nQYRSGAAPQPGPAHLSLTITLLMTARLWGGTLLWT\n\n","organism":"Homo sapiens","uniprot_code":"Q03405","uniprot_range_first":null,"uniprot_range_last":null,"oligomerization":"monomer","molecular_type":"protein","uniprot_sequence":"MGHPPLLPLLLLLHTCVPASWGLRCMQCKTNGDCRVEECALGQDLCRTTIVRLWEEGEEL\nELVEKSCTHSEKTNRTLSYRTGLKITSLTEVVCGLDLCNQGNSGRAVTYSRSRYLECISC\nGSSDMSCERGRHQSLQCRSPEEQCLDVVTHWIQEGEEGRPKDDRHLRGCGYLPGCPGSNG\nFHNNDTFHFLKCCNTTKCNEGPILELENLPQNGRQCYSCKGNSTHGCSSEETFLIDCRGP\nMNQCLVATGTHEPKNQSYMVRGCATASMCQHAHLGDAFSMNHIDVSCCTKSGCNHPDLDV\nQYRSGAAPQPGPAHLSLTITLLMTARLWGGTLLWT","mw":36.98,"total_mw":36.98,"number_molecules":1,"complex_state":null,"deuteration":null,"molecule_source":"biological","molecule_description":null}],"buffer":{"name":"25 mM Sodium Phosphate 5 % Glycerol 50 mM NaSO4","concentration_unit":"mM","comment":null,"additive":"Glycerol 5.000 %, NaSO4 50.000 mM","concentration":25.0,"pka":null,"ph":7.2,"deuteration":null},"purity_method":null,"name":"uPAR H47C/N259C","ext_coefficient":null,"contrast":null,"specific_vol":null,"dry_vol":null,"absorbption":null,"deuteration":null,"mixture":null},"contributor":[{"affiliation":[{"short_name":"EMBL-Hamburg","address":"Notkestraße 85, Geb. 25A, 22607 Hamburg, Deutschland, Germany","full_name":"European Molecular Biology Laboratory (EMBL) - Hamburg outstation","webpage":"http://www.embl-hamburg.de/index.php"}],"contributor_name":"Haydyn","contributor_surname":"Mertens","orcid":null}],"concentration_method":"A280","concentration_unit":"mg/ml","date":"2010-06-10","storage_temperature":10.0,"cell_temperature":10.0,"exposure_time":30.0,"number_of_frames":4,"wavelength":0.15,"sample_detector_distance":2.7,"concentration_min":1.5,"concentration_max":4.4,"sample_volume":null,"flow_rate":null,"s_min":0.067,"s_max":6.345,"total_exposure_time":null,"seccolumn":null},"fits":[{"models":[{"model_plot":"https://www.sasbdb.org/media/pdb_file/images/SASDAU4_fit1_model1_img.png","software":"DAMMIF","pdb_link":[],"model_title":null,"type_of_model":"dummy","software_version":"","model_data":"https://www.sasbdb.org/media/pdb_file/SASDAU4_fit1_model1.pdb","model_mw":null,"bead_radius":1.9,"log":null,"symmetry":"P1","comment":"","user":12}],"fit_unit":"1/A","fit_plot":"https://www.sasbdb.org/media/fitting_files/scattering_plots/SASDAU4_fit1_fit_img.png","software":null,"chi_square_value":2.217121,"p_value":1.4e-05,"fit_residual_plot":"SASDAU4_fit1_fitresiduals_img.png","fit_data":"https://www.sasbdb.org/media/fitting_files/SASDAU4_fit1.fir","fit_log":null,"software_version":null,"description":null},{"models":[{"model_plot":"https://www.sasbdb.org/media/pdb_file/images/SASDAU4_fit2_model1_img.png","software":"CORAL","pdb_link":[],"model_title":null,"type_of_model":"mix","software_version":"","model_data":"https://www.sasbdb.org/media/pdb_file/SASDAU4_fit2_model1.pdb","model_mw":33.29,"bead_radius":1.9,"log":null,"symmetry":"P1","comment":"","user":12}],"fit_unit":"1/A","fit_plot":"https://www.sasbdb.org/media/fitting_files/scattering_plots/SASDAU4_fit2_fit_img.png","software":null,"chi_square_value":1.787569,"p_value":0.003397,"fit_residual_plot":"SASDAU4_fit2_fitresiduals_img.png","fit_data":"https://www.sasbdb.org/media/fitting_files/SASDAU4_fit2.fit","fit_log":null,"software_version":null,"description":null}],"estimated_volume_method":null,"pddf_software":"ATSAS GNOM","pddf_software_version":null,"i0_calibration_standard":"BSA","description":null,"experiment_description":null,"tags":["X33"],"intensity_unit":null,"experimental_mw":34.0,"experimental_mw_error":null,"guinier_i0_mw":34.0,"guinier_i0_mw_error":null,"porod_mw":null,"porod_mw_error":null,"pddf_i0":null,"pddf_i0_error":null,"guinier_i0":36.7,"guinier_i0_error":null,"pddf_rg":2.2,"pddf_rg_error":null,"guinier_rg":2.2,"guinier_rg_error":null,"pddf_dmax":7.0,"pddf_dmax_error":null,"porod_volume":57.0,"porod_volume_error":null,"estimated_volume":null,"estimated_volume_error":null,"guinier_point_first":48,"guinier_point_last":192,"pddf_point_first":48,"pddf_point_last":1200,"i0_calibration_standard_data":null,"intensities_log_log_plot":"SASDAU4_datloglog_img.png","symmetry":null,"last_modified":"2023-05-25T11:21:52.654103+02:00","bragg_peak":[]}