{"code":"SASDDU8","status":"Published","type_of_curve":"SEC-SAS","angular_unit":"1/A","project":{"title":"Multidomain architecture of estrogen receptor reveals interfacial cross-talk between its DNA-binding and ligand-binding domains.","publication":{"title":"Multidomain architecture of estrogen receptor reveals interfacial cross-talk between its DNA-binding and ligand-binding domains.","author_list":"Huang W, Peng Y, Kiselar J, Zhao X, Albaqami A, Mendez D, Chen Y, Chakravarthy S, Gupta S, Ralston C, Kao HY, Chance MR, Yang S","journal":"Nat Commun","doi":"10.1038/s41467-018-06034-2","pmid":"30166540","published_date":"2018 Aug 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University","webpage":"https://case.edu/"}],"contributor_name":"Sichun","contributor_surname":"Yang","orcid":null}],"concentration_method":null,"concentration_unit":null,"date":"2014-08-10","storage_temperature":4.0,"cell_temperature":10.0,"exposure_time":1.1,"number_of_frames":20,"wavelength":0.103,"sample_detector_distance":3.0,"concentration_min":0.1,"concentration_max":0.8,"sample_volume":null,"flow_rate":null,"s_min":0.171,"s_max":2.468,"total_exposure_time":null,"seccolumn":null},"fits":[{"models":[{"model_plot":"https://www.sasbdb.org/media/pdb_file/images/SASDDU8_fit1_model1_img.png","software":"Custom 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from solutions of the multi-component estrogen receptor in 10 mM CHES, 125 mM NaCl, 5mM KCl, 4 mM MgCl2, 50 mM arginine, 50 mM glutamate, 5 mM TCEP, 5% glycerol, 10 µm Zn acetate, 10 µM estradiol, pH 9.5 were collected on the BioCAT 18ID beam line at the Advanced Photon Source (APS; Argonne, IL, USA) using a MAR 165 CCD detector at a sample-detector distance of 3 m and at a wavelength of λ = 0.103 nm (l(s) vs s, where s = 4πsinθ/λ, and 2θ is the scattering angle). Solute concentrations ranging between 0.1 and 0.8 mg/ml were measured at 10°C from size-exclusion chromatography eluates. 20 successive 1.100 second frames were collected. 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