{"code":"SASDXK6","status":"Published","type_of_curve":"Single concentration","angular_unit":"1/nm","project":{"title":"CD2AP’s Structure and Oligomerization are compromised by the K301M mutation: implications for Nephrotic syndrome","publication":null,"status":"released","submitted_date":"2025-07-16","released_date":"2026-05-09"},"pddf_data":"https://www.sasbdb.org/media/p_of_R_files/SASDXK6.out","intensities_data":"https://www.sasbdb.org/media/intensities_files/SASDXK6.dat","intensities_log_plot":"https://www.sasbdb.org/media/intensities_files/scattering_plots/SASDXK6_dat_img.png","intensities_kratky_plot":"https://www.sasbdb.org/media/intensities_files/scattering_plots/SASDXK6_kratky_img.png","pddf_plot":"https://www.sasbdb.org/media/p_of_R_files/pofr_images/SASDXK6_pofr_img.png","intensities_guinier_plot":"https://www.sasbdb.org/media/intensities_files/scattering_plots/SASDXK6_guinier_img.png","sascif_data":"https://www.sasbdb.org/media/sascif/sascif_files/SASDXK6.sascif","experiment":{"instrument":{"detector":{"type":"Hybrid Photon Counting (HPC)","name":"Mythen2 R 1K","resolution":null},"name":"CSIR-Central Drug Research Institute","city":"Lucknow","country":"India","beamline_name":"Anton Paar SAXSpace","beam_geometry":null,"type_of_source":"X-ray in house","point_source":null,"line_collimation":null,"sample_path_length":null,"line_collimation_slitlength":null,"line_collimation_integrationwidth":null,"xray_energy":null,"beam_profile_ah":null,"beam_profile_al":null},"sample":{"molecule":[{"long_name":"CD2-associated protein","short_name":null,"sequence":"MVDYIVEYDYDAVHDDELTIRVGEIIRNVKKLQEEGWLEGELNGRRGMFPDNFVKEI\r\nKRETEFKDDSLPIKRERHGNVASLVQRISTYGLPAGGIQPHPQTKNIKKKTKKRQCK\r\nVLFEYIPQNEDELELKVGDIIDINEEVEEGWWSGTLNNKLGLFPSNFVKELEVTDDG\r\nETHEAQDDSETVLAGPTSPIPSLGNVSETASGSVTQPKKIRGIGFGDIFKEGSVKLR\r\nTRTSSSETEEKKPEKPLILQSLGPKTQSVEITKTDTEGKIRAKEYCRTLFAYEGTNED\r\nELTFKEGEIIHLISMETGEAGWWRGELNGKEGVFPDNFAVQINELDKDFPKPKKPPP\r\nPAKAPAPKPELIAAEKKYFSLKPEEKDEKSTLEQKPSKPAAPQVPPKKPTPPTKASN\r\nLLRSSGTVYPKRPEKPVPPPPPIAKINGEVSSISSKFETEPVSKLKLDSEQLPLRPKS\r\nVDFDSLTVRTSKETDVVNFDDIASSENLLHLTANRPKMPGRRLPGRFNGGHSPTHS\r\nPEKILKLPKEEDSANLKPSELKKDTCYSPKPSVYLSTPSSASKANTTAFLTPLEIKAK\r\nVETDDVKKNSLDELRAQIIELLCIVEALKKDHGKELEKLRKDLEEEKTMRSNLEMEIE\r\nKLKKAVLSS","organism":"Homo sapiens","uniprot_code":"Q9Y5K6","uniprot_range_first":null,"uniprot_range_last":null,"oligomerization":"trimer","molecular_type":"protein","uniprot_sequence":"MVDYIVEYDYDAVHDDELTIRVGEIIRNVKKLQEEGWLEGELNGRRGMFPDNFVKEIKRE\nTEFKDDSLPIKRERHGNVASLVQRISTYGLPAGGIQPHPQTKNIKKKTKKRQCKVLFEYI\nPQNEDELELKVGDIIDINEEVEEGWWSGTLNNKLGLFPSNFVKELEVTDDGETHEAQDDS\nETVLAGPTSPIPSLGNVSETASGSVTQPKKIRGIGFGDIFKEGSVKLRTRTSSSETEEKK\nPEKPLILQSLGPKTQSVEITKTDTEGKIKAKEYCRTLFAYEGTNEDELTFKEGEIIHLIS\nKETGEAGWWRGELNGKEGVFPDNFAVQINELDKDFPKPKKPPPPAKAPAPKPELIAAEKK\nYFSLKPEEKDEKSTLEQKPSKPAAPQVPPKKPTPPTKASNLLRSSGTVYPKRPEKPVPPP\nPPIAKINGEVSSISSKFETEPVSKLKLDSEQLPLRPKSVDFDSLTVRTSKETDVVNFDDI\nASSENLLHLTANRPKMPGRRLPGRFNGGHSPTHSPEKILKLPKEEDSANLKPSELKKDTC\nYSPKPSVYLSTPSSASKANTTAFLTPLEIKAKVETDDVKKNSLDELRAQIIELLCIVEAL\nKKDHGKELEKLRKDLEEEKTMRSNLEMEIEKLKKAVLSS","mw":71.481,"total_mw":214.443,"number_molecules":3,"complex_state":false,"deuteration":null,"molecule_source":"biological","molecule_description":"It is the mutant form is Human CD2AP"}],"buffer":{"name":"10 mM potassium phosphate","concentration_unit":null,"comment":null,"additive":null,"concentration":null,"pka":null,"ph":7.6,"deuteration":null},"purity_method":null,"name":"CD2-associated protein (CD2AP) K301M point mutant","ext_coefficient":null,"contrast":null,"specific_vol":null,"dry_vol":null,"absorbption":null,"deuteration":null,"mixture":null},"contributor":[{"affiliation":[{"short_name":null,"address":null,"full_name":"university of Hyderabad India ","webpage":null}],"contributor_name":"Anil Kumar","contributor_surname":"Pasupulati et .al","orcid":"https://orcid.org/0000-0001-9467-7650"}],"concentration_method":null,"concentration_unit":null,"date":"2025-05-18","storage_temperature":10.0,"cell_temperature":10.0,"exposure_time":900.0,"number_of_frames":4,"wavelength":0.514,"sample_detector_distance":0.317,"concentration_min":null,"concentration_max":7.0,"sample_volume":null,"flow_rate":null,"s_min":0.084,"s_max":7.782,"total_exposure_time":null,"seccolumn":null},"fits":[],"estimated_volume_method":null,"pddf_software":"ATSAS GNOM","pddf_software_version":"5.0","i0_calibration_standard":null,"description":"mutant of CD2AP, First eleven points removed for display purposes. 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