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2 hits found for Yang

SASDDU8 – Multidomain architecture of the estrogen receptor reveals interfacial cross-talk between its DNA-binding and ligand-binding domains

Estrogen receptorERE1ERE2EstradiolhERa peptide1hERa peptide2 experimental SAS data
CUSTOM IN-HOUSE model
Sample: Estrogen receptor dimer, None protein
ERE1 monomer, Homo sapiens DNA
ERE2 monomer, Homo sapiens DNA
Estradiol , None other
hERa peptide1 monomer, None protein
hERa peptide2 monomer, None protein
Buffer: 10 mM CHES (pH9.5), 125 mM NaCl, 5mM KCl, 4 mM MgCl2, 50 mM arginine, 50 mM glutamate, 5 mM TCEP, 5% glycerol, 10 µm Zn acetate, 10 µM estradiol, pH: 9.5
Experiment: SAXS data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2014 Aug 10
Multidomain architecture of estrogen receptor reveals interfacial cross-talk between its DNA-binding and ligand-binding domains. Nat Commun 9(1):3520 (2018)
...Yang S
RgGuinier 3.8 nm
Dmax 11.5 nm

SASDEE2 – The N-terminal domain of estrogen receptor alpha

The N-terminal domain of estrogen receptor alpha experimental SAS data
CUSTOM IN-HOUSE model
Sample: The N-terminal domain of estrogen receptor alpha monomer, Homo sapiens protein
Buffer: 20 mM sodium phosphate, 50 mM NaCl, 0.05 mM TCEP, pH: 7.4
Experiment: SAXS data collected at 16-ID (LiX), National Synchrotron Light Source (NSLS-II) on 2017 Jun 12
A Metastable Contact and Structural Disorder in the Estrogen Receptor Transactivation Domain Structure (2018)
...Yang L, Chance M, Surewicz W, Buck M, Yang S
RgGuinier 3.0 nm
Dmax 10.0 nm