SASBDB entries for UniProt ID: P0DTC1

SASDJG5 – SARS-CoV-2 Main Protease

UniProt ID: P0DTC1 (3264-3569) 3C-like proteinase from SARS-CoV-2 replicase polyprotein 1a

3C-like proteinase from SARS-CoV-2 replicase polyprotein 1a experimental SAS data
PDB model
Sample: 3C-like proteinase from SARS-CoV-2 replicase polyprotein 1a dimer, 68 kDa Severe acute respiratory … protein
Buffer: 50 mM Tris, 1 mM DTT, 1 mM EDTA, pH: 7.4
Experiment: SAXS data collected at Rigaku BioSAXS-2000, University of British Columbia on 2020 Jun 1
COVID Main Protease
Nathanael Caveney
RgGuinier 2.7 nm
Dmax 8.8 nm
VolumePorod 93 nm3

SASDKJ4 – SARS-CoV-2 nsp7 and nsp8

UniProt ID: P0DTC1 (3860-3942) Replicase polyprotein 1a - nsp7

UniProt ID: P0DTC1 (3943-4140) Replicase polyprotein 1a - nsp8

Replicase polyprotein 1a - nsp7Replicase polyprotein 1a - nsp8 experimental SAS data
PDB model
Sample: Replicase polyprotein 1a - nsp7, 18 kDa Severe acute respiratory … protein
Replicase polyprotein 1a - nsp8, 44 kDa Severe acute respiratory … protein
Buffer: 50 mM Tris, pH 8.0, 100 mM NaCl, 4 mM DTT, 4 mM MgCl2, pH: 8
Experiment: SAXS data collected at EMBL P12, PETRA III on 2020 Jun 19
Hallmarks of Alpha- and Betacoronavirus non-structural protein 7+8 complexes Science Advances 7(10):eabf1004 (2021)
Krichel B, Bylapudi G, Schmidt C, Blanchet C, Schubert R, Brings L, Koehler M, Zenobi R, Svergun D, Lorenzen K, Madhugiri R, Ziebuhr J, Uetrecht C
RgGuinier 3.4 nm
Dmax 13.5 nm
VolumePorod 92 nm3