Curated repository for small angle scattering data and models


SASBDB currently contains:


4996

experimental data sets

6230

models
507 experimental data sets on hold
690 models on hold

Small angle scattering (SAS) of X-ray and neutrons provides structural information on biological macromolecules in solution at a resolution of 1-2 nm.
SASBDB is a fully searchable curated repository of freely accessible and downloadable experimental data, which are deposited together with the relevant experimental conditions, sample details, derived models and their fits to the data.

Recent depositions:

SASDXK2 – Enabled/vasodilator-stimulated phosphoprotein homology 1 domain (EVH1) from Mus musculus Homer1

EVH1 domain of Homer protein homolog 1 from mouse experimental SAS data
XPLOR-NIH model
Sample: EVH1 domain of Homer protein homolog 1 from mouse monomer, 14 kDa Mus musculus protein
Buffer: 20mM NaCl, 50 mM NaPi, 0.02% of sodium-azide, pH: 7.4
Experiment: SAXS data collected at Rigaku BioSAXS-2000, CEITEC on 2023 Nov 9
Structural Modeling and Dynamics of the Full-Length Homer1 Multimer. Proteins (2025)
Kálmán ZE, Czajlik A, Maruzs B, Farkas F, Pap I, Homonnay C, Klumpler T, Batta G, Gáspári Z, Péterfia B
RgGuinier 1.6 nm
Dmax 5.3 nm
VolumePorod 23 nm3

SEC-SAXS data of wildtype Melanotaenia fluviatilis apo estrogen receptor alpha ligand binding domain (LBD) at pH 7.5
Estrogen receptor alpha experimental SAS data
A ternary switch model governing ERα ligand binding domain conformation. Nat Commun 2025 Nov 24;16(1):10363
Nat Commun 16(1):10363 (2025 Nov 24)
Mammalian translation elongation factor eEF1A1
Mammalian translation elongation factor eEF1A1 experimental SAS data
Dynamics and structural features of the eEF1A1 and eEF1A2 paralogs Nucleic Acids Research 2025 Nov 13 53(21)
Nucleic Acids Research 53(21) (2025 Nov 13)
Entamoeba histolytica Anti-Silencing Function 1 (ASF1) with C terminal His6-tag
Anti-Silencing Function 1 experimental SAS data
Characterisation of Entamoeba histolytica Anti-Silencing Function 1 as a histone chaperone. Biochimie 2025 Nov 11;
Biochimie (2025 Nov 11)
N-acetylmuramoyl-L-alanine amidase (without His-Tag)
N-acetylmuramoyl-L-alanine amidase experimental SAS data
Dissecting the molecular basis underlying mycobacterial cell-wall hydrolysis by the catalytic domains of D29LysA and DS6ALysA phage endolysins. Int J Biol Macromol 2025 Nov 7;:148896
Int J Biol Macromol :148896 (2025 Nov 7)
K214/R260 mutant of Rabies virus CVS Phosphoprotein Isoform 3 (KRm CVS P3)
Phosphoprotein (Isoform P3; K214A, R260A, D289N, C297S) experimental SAS data
Conformational dynamics, RNA binding, and phase separation regulate the multifunctionality of rabies virus P protein. Nat Commun 2025 Oct 29;16(1):9491
Nat Commun 16(1):9491 (2025 Oct 29)

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To cite SASBDB refer to: Kikhney AG, Borges CR, Molodenskiy DS, Jeffries CM, Svergun DI (2020) SASBDB: Towards an automatically curated and validated repository for biological scattering data. Protein Science 29(1); 66-75.