Proteins involved in sleep homeostasis: Biophysical characterization of INC and its partners

Pirone L, Smaldone G, Esposito C, Balasco N, Petoukhov M, Spilotros A, Svergun D, Di Gaetano S, Vitagliano L, Pedone E
Biochimie 131:106-114 (2016 Dec)

doi: 10.1016/j.biochi.2016.09.013

Submitted to SASBDB: 2021 Apr 23 Published in SASBDB: 2021 Apr 24

SASDLN4 – Insomniac protein (INC) – cullin 3 complex Sample: Cullin 3 pentamer, 60 kDa Drosophila melanogaster protein Insomniac protein pentamer, 210 kDa Drosophila melanogaster protein Buffer: 50 mM TrisHCl, 300 mM NaCl, 2 mM DTT, pH: 8 Experiment: SAXS data collected at B21, Diamond Light Source on 2014 Nov 24 RgGuinier 6.7 nm Dmax 25.2 nm