The C-Terminal Random Coil Region Tunes the Ca2+-Binding Affinity of S100A4 through Conformational Activation

Duelli A, Kiss B, Lundholm I, Bodor A, Petoukhov M, Svergun D, Nyitray L, Katona G, Csernoch L
PLoS ONE 9(5):e97654 (2014 May 15)

doi: 10.1371/journal.pone.0097654
Submitted to SASBDB: 2021 Apr 28
Published in SASBDB:

SASDLW4 – Human Protein S100-A4

Protein S100-A4 experimental SAS data
EOM/RANCH model
Sample: Protein S100-A4 dimer, 23 kDa Homo sapiens protein
Buffer: 20 mM HEPES, 20 mM NaCl, 0.1 mM TCEP, pH: 7.5
Experiment: SAXS data collected at BM29, ESRF on 2013 Mar 2
RgGuinier 2.1 nm
Dmax 7.0 nm
VolumePorod 48 nm3