Conformation of full-length Bruton tyrosine kinase (Btk) from synchrotron X-ray solution scattering.

Márquez JA, Smith CI, Petoukhov MV, Lo Surdo P, Mattsson PT, Knekt M, Westlund A, Scheffzek K, Saraste M, Svergun DI
EMBO J 22(18):4616-24 (2003 Sep 15)
PMID: 12970174
doi: 10.1093/emboj/cdg448 		Submitted to SASBDB: 2017 Feb 9
Published in SASBDB:

SASDC52 – Bruton tyrosine kinase

Tyrosine-protein kinase BTK (R28C mutant) experimental SAS data
GASBOR model
Sample: Tyrosine-protein kinase BTK (R28C mutant) monomer, 76 kDa Homo sapiens protein
Buffer: 20 mM HEPES 200 mM NaCl, 2 mM DTT and 1 mM MgCl2, pH: 7.5
Experiment: SAXS data collected at EMBL X33, DORIS III, DESY on 2002 Apr 2
RgGuinier 5.0 nm
Dmax 20.0 nm
VolumePorod 130 nm3