Browse by MACROMOLECULE type: protein

SASDWC9 – Proliferating cell nuclear antigen:PCNA-associated factor (PCNA:P15) titration, 150 µM:150 µM

Proliferating cell nuclear antigenPCNA-associated factor experimental SAS data
Proliferating cell nuclear antigen PCNA-associated factor Kratky plot
Sample: Proliferating cell nuclear antigen trimer, 87 kDa Homo sapiens protein
PCNA-associated factor monomer, 12 kDa Homo sapiens protein
Buffer: 137 mM NaCl, 2.7 mM KCl, 10 mM sodium phosphate, 2 mM potassium phosphate (PBS), pH: 7
Experiment: SAXS data collected at EMBL P12, PETRA III on 2012 Apr 23
KDSAXS: A tool for Analyzing Binding Equilibria with SAXS Data using Explicit Models Journal of Molecular Biology :169103 (2025)
Gomes T, Ruiz L, Martin-Malpartida P, Bernadó P, Baptista A, Macias M, Cordeiro T
RgGuinier 3.7 nm
Dmax 11.0 nm
VolumePorod 219 nm3

SASDWD9 – Proliferating cell nuclear antigen:PCNA-associated factor (PCNA:P15) titration, 150 µM:200 µM

Proliferating cell nuclear antigenPCNA-associated factor experimental SAS data
Proliferating cell nuclear antigen PCNA-associated factor Kratky plot
Sample: Proliferating cell nuclear antigen trimer, 87 kDa Homo sapiens protein
PCNA-associated factor monomer, 12 kDa Homo sapiens protein
Buffer: 137 mM NaCl, 2.7 mM KCl, 10 mM sodium phosphate, 2 mM potassium phosphate (PBS), pH: 7
Experiment: SAXS data collected at EMBL P12, PETRA III on 2012 Apr 23
KDSAXS: A tool for Analyzing Binding Equilibria with SAXS Data using Explicit Models Journal of Molecular Biology :169103 (2025)
Gomes T, Ruiz L, Martin-Malpartida P, Bernadó P, Baptista A, Macias M, Cordeiro T
RgGuinier 3.7 nm
Dmax 11.0 nm
VolumePorod 208 nm3

SASDWE9 – Proliferating cell nuclear antigen:PCNA-associated factor (PCNA:P15) titration, 150 µM:300 µM

Proliferating cell nuclear antigenPCNA-associated factor experimental SAS data
Proliferating cell nuclear antigen PCNA-associated factor Kratky plot
Sample: Proliferating cell nuclear antigen trimer, 87 kDa Homo sapiens protein
PCNA-associated factor monomer, 12 kDa Homo sapiens protein
Buffer: 137 mM NaCl, 2.7 mM KCl, 10 mM sodium phosphate, 2 mM potassium phosphate (PBS), pH: 7
Experiment: SAXS data collected at EMBL P12, PETRA III on 2012 Apr 23
KDSAXS: A tool for Analyzing Binding Equilibria with SAXS Data using Explicit Models Journal of Molecular Biology :169103 (2025)
Gomes T, Ruiz L, Martin-Malpartida P, Bernadó P, Baptista A, Macias M, Cordeiro T
RgGuinier 3.9 nm
Dmax 11.5 nm
VolumePorod 194 nm3

SASDWF9 – Proliferating cell nuclear antigen:PCNA-associated factor (PCNA:P15) titration, 150 µM:370 µM

Proliferating cell nuclear antigenPCNA-associated factor experimental SAS data
Proliferating cell nuclear antigen PCNA-associated factor Kratky plot
Sample: Proliferating cell nuclear antigen trimer, 87 kDa Homo sapiens protein
PCNA-associated factor monomer, 12 kDa Homo sapiens protein
Buffer: 137 mM NaCl, 2.7 mM KCl, 10 mM sodium phosphate, 2 mM potassium phosphate (PBS), pH: 7
Experiment: SAXS data collected at EMBL P12, PETRA III on 2012 Apr 23
KDSAXS: A tool for Analyzing Binding Equilibria with SAXS Data using Explicit Models Journal of Molecular Biology :169103 (2025)
Gomes T, Ruiz L, Martin-Malpartida P, Bernadó P, Baptista A, Macias M, Cordeiro T
RgGuinier 3.7 nm
Dmax 11.0 nm
VolumePorod 187 nm3

SASDVX3 – Desulfofustis sp. PB-SRB1 ligand-gated ion channel DeCLIC with calcium at pH 5 by paused SEC-SANS

Neurotransmitter-gated ion-channel ligand-binding domain-containing protein experimental SAS data
Desulfofustis sp. PB-SRB1 ligand-gated ion channel DeCLIC with calcium at pH 5 by paused SEC-SANS Rg histogram
Sample: Neurotransmitter-gated ion-channel ligand-binding domain-containing protein pentamer, 342 kDa Desulfofustis sp. PB-SRB1 protein
Buffer: 20 mM citrate, 150 mM NaCl, 10 mM CaCl2, 0.5 mM deuterated n-Dodecyl-B-D-Maltoside, in D2O, pH: 5
Experiment: SANS data collected at D22, Institut Laue-Langevin (ILL) on 2021 Jun 17
Structural characterization of pH-modulated closed and open states in a pentameric ligand-gated ion channel
Marie Lycksell
RgGuinier 5.1 nm
Dmax 17.1 nm
VolumePorod 581 nm3

SASDVY3 – Desulfofustis sp. PB-SRB1 ligand-gated ion channel DeCLIC without calcium at pH 5 by paused SEC-SANS

Neurotransmitter-gated ion-channel ligand-binding domain-containing protein experimental SAS data
Desulfofustis sp. PB-SRB1 ligand-gated ion channel DeCLIC without calcium at pH 5 by paused SEC-SANS Rg histogram
Sample: Neurotransmitter-gated ion-channel ligand-binding domain-containing protein pentamer, 342 kDa Desulfofustis sp. PB-SRB1 protein
Buffer: 20 mM citrate, 150 mM NaCl, 10 mM EDTA, 0.5 mM deuterated n-Dodecyl-β-D-Maltoside, in D2O, pH: 5
Experiment: SANS data collected at D22, Institut Laue-Langevin (ILL) on 2021 Jun 17
Structural characterization of pH-modulated closed and open states in a pentameric ligand-gated ion channel
Marie Lycksell
RgGuinier 5.2 nm
Dmax 18.4 nm
VolumePorod 558 nm3

SASDWF4 – Outer membrane protein MIP from Legionella pneumophila (LpMIP) in complex with inhibitor NJS224

Outer membrane protein MIP(2S)‐2‐{[(2S)‐1‐[(4‐ fluorophenyl)methanesulfonyl]piperidin‐2‐ yl]formamido}‐4‐methyl‐N‐[(pyridin‐3‐ yl)methyl]pentanamide experimental SAS data
SREFLEX model
Sample: Outer membrane protein MIP dimer, 46 kDa Legionella pneumophila subsp. … protein
(2S)‐2‐{[(2S)‐1‐[(4‐ fluorophenyl)methanesulfonyl]piperidin‐2‐ yl]formamido}‐4‐methyl‐N‐[(pyridin‐3‐ yl)methyl]pentanamide monomer, 1 kDa
Buffer: 20 mM Tris, 150 mM NaCl, pH: 7.5
Experiment: SAXS data collected at EMBL P12, PETRA III on 2021 Nov 22
Structure and Dynamics of Macrophage Infectivity Potentiator Proteins from Pathogenic Bacteria and Protozoans Bound to Fluorinated Pipecolic Acid Inhibitors. J Med Chem (2025)
Pérez Carrillo VH, Whittaker JJ, Wiedemann C, Harder JM, Lohr T, Jamithireddy AK, Dajka M, Goretzki B, Joseph B, Guskov A, Harmer NJ, Holzgrabe U, Hellmich UA
RgGuinier 2.9 nm
Dmax 9.7 nm
VolumePorod 61 nm3

SASDWG4 – Outer membrane protein MIP from Legionella pneumophila (LpMIP) in complex with inhibitor NJS227

Outer membrane protein MIP(2S)‐3‐(4‐fluorophenyl)‐2‐{[(2S)‐1‐[(4‐ fluorophenyl)methanesulfonyl]piperidin‐2‐ yl]formamido}‐N‐[(pyridin‐3‐yl)methyl]propanamide experimental SAS data
SREFLEX model
Sample: Outer membrane protein MIP dimer, 46 kDa Legionella pneumophila subsp. … protein
(2S)‐3‐(4‐fluorophenyl)‐2‐{[(2S)‐1‐[(4‐ fluorophenyl)methanesulfonyl]piperidin‐2‐ yl]formamido}‐N‐[(pyridin‐3‐yl)methyl]propanamide monomer, 1 kDa
Buffer: 20 mM Tris, 150 mM NaCl, pH: 7.5
Experiment: SAXS data collected at EMBL P12, PETRA III on 2021 Nov 22
Structure and Dynamics of Macrophage Infectivity Potentiator Proteins from Pathogenic Bacteria and Protozoans Bound to Fluorinated Pipecolic Acid Inhibitors. J Med Chem (2025)
Pérez Carrillo VH, Whittaker JJ, Wiedemann C, Harder JM, Lohr T, Jamithireddy AK, Dajka M, Goretzki B, Joseph B, Guskov A, Harmer NJ, Holzgrabe U, Hellmich UA
RgGuinier 3.0 nm
Dmax 10.0 nm
VolumePorod 65 nm3

SASDVK4 – Immunoglobulin light chain AL55

Immunoglobulin light chain AL55 experimental SAS data
SWISSMODEL model
Sample: Immunoglobulin light chain AL55 dimer, 47 kDa Homo sapiens protein
Buffer: 20 mM TrisHCL, 150 mM NaCl, pH: 8
Experiment: SAXS data collected at BM29, ESRF on 2022 Jan 15
A conformational fingerprint for amyloidogenic light chains eLife 13 (2025)
Paissoni C, Puri S, Broggini L, Sriramoju M, Maritan M, Russo R, Speranzini V, Ballabio F, Nuvolone M, Merlini G, Palladini G, Hsu S, Ricagno S, Camilloni C
RgGuinier 2.6 nm
Dmax 8.5 nm
VolumePorod 61 nm3

SASDVL4 – Immunoglobulin light chain H3

Immunoglobulin light chain H3 experimental SAS data
MODELLER model
Sample: Immunoglobulin light chain H3 dimer, 45 kDa Homo sapiens protein
Buffer: 20 mM TrisHCL, 150 mM NaCl, pH: 8
Experiment: SAXS data collected at EMBL P12, PETRA III on 2018 May 12
A conformational fingerprint for amyloidogenic light chains eLife 13 (2025)
Paissoni C, Puri S, Broggini L, Sriramoju M, Maritan M, Russo R, Speranzini V, Ballabio F, Nuvolone M, Merlini G, Palladini G, Hsu S, Ricagno S, Camilloni C
RgGuinier 2.6 nm
Dmax 8.4 nm
VolumePorod 56 nm3