Curated repository for small angle scattering data and models


SASBDB currently contains:


1414

experimental data sets

2235

models
361 experimental data sets on hold
316 models on hold

Small angle scattering (SAS) of X-ray and neutrons provides structural information on biological macromolecules in solution at a resolution of 1-2 nm.
SASBDB is a fully searchable curated repository of freely accessible and downloadable experimental data, which are deposited together with the relevant experimental conditions, sample details, derived models and their fits to the data.

Recent depositions:

SASDEW7 – C-terminal truncated bank vole prion protein (amino acids 90-231)

Major prion protein experimental SAS data
C-terminal truncated bank vole prion protein (amino acids 90-231) Rg histogram
Sample: Major prion protein monomer, 16 kDa Myodes glareolus protein
Buffer: 25 mM Ammonium Acetate, 250 mM NaCl, pH: 5.5
Experiment: SAXS data collected at BM29, ESRF on 2018 Feb 25
Deciphering Copper Coordination in the Mammalian Prion Protein Amyloidogenic Domain Biophysical Journal (2020)
Salzano G, Brennich M, Mancini G, Tran T, Legname G, D’Angelo P, Giachin G
RgGuinier 2.3 nm
Dmax 9.4 nm
VolumePorod 29 nm3

SASDH44 – 3' Complex of XPA-DBD and RPA70AB
DNA repair protein complementing XP-A cellsReplication protein A 70 kDa DNA-binding subunit3-prime Nucleotide Excision Repair Junction Model Substrate experimental SAS data
HADDOCK model
A key interaction with RPA orients XPA in NER complexes.
SASDHC3 – Braveheart in 0 mM MgCl2
Braveheart RNA experimental SAS data
DAMMIN model
Zinc-finger protein CNBP alters the 3-D structure of lncRNA Braveheart in solution
SASDEN8 – Intracellular region of the human Cyclin and CBS domain divalent metal cation transport mediator-4 in complex with Phosphatase of Regenerating Liver-1 and MgATP
CNNM4_BAT-cNMP-CtailProtein tyrosine phosphatase type IVA 1 experimental SAS data
CORAL model
Structural Insights into the Intracellular Region of the Human Magnesium Transport Mediator CNNM4.
SASDCQ6 – Rap guanine nucleotide exchange factor 3 (isoform3) - apo form
Rap guanine nucleotide exchange factor 3 experimental SAS data
SWISSMODEL model
Conformational States of Exchange Protein Directly Activated by cAMP (EPAC1) Revealed by Ensemble Modeling and Integrative Structural Biology.
SASDF55 – Leukocidin (LukGH) from Staphylococcus aureus in complex with a neutralizing antibody
Leukocidin GLeukocidin HLukGH neutralizing antibody experimental SAS data
PDB model
Molecular mechanism of leukocidin GH-integrin CD11b/CD18 recognition and species specificity.

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