Curated repository for small angle scattering data and models


SASBDB currently contains:


1617

experimental data sets

2552

models
444 experimental data sets on hold
417 models on hold

Small angle scattering (SAS) of X-ray and neutrons provides structural information on biological macromolecules in solution at a resolution of 1-2 nm.
SASBDB is a fully searchable curated repository of freely accessible and downloadable experimental data, which are deposited together with the relevant experimental conditions, sample details, derived models and their fits to the data.

Recent depositions:

SASDHT8 – Complex of mosquito-larvicidal BinB protein and the Mosquito-larvicidal binary toxin receptor (Cqm1)

Binary larvicide subunit BinBSynthetic construct (mutant, His-tagged): Mosquito-larvicidal BinAB toxin receptor protein (Neutral and basic amino acid transport protein rBAT) experimental SAS data
OTHER model
Sample: Binary larvicide subunit BinB monomer, 53 kDa Lysinibacillus sphaericus protein
Synthetic construct (mutant, His-tagged): Mosquito-larvicidal BinAB toxin receptor protein (Neutral and basic amino acid transport protein rBAT) monomer, 65 kDa Culex quinquefasciatus protein
Buffer: PBS buffer (10 mM Na2HPO4, 1.8 mM KH2PO4, 137 mM NaCl, 2.7 mM KCl), pH: 7.4
Experiment: SAXS data collected at BL-18, INDUS-2 on 2020 Feb 24
Liposome-Based Study Provides Insight into Cellular Internalization Mechanism of Mosquito-Larvicidal BinAB Toxin. J Membr Biol (2020)
Sharma M, Kumar A, Kumar V
RgGuinier 4.6 nm
Dmax 11.7 nm
VolumePorod 290 nm3

Collagen VI von Willebrand factor (VWA) double-domain fragment, N5N4
Collagen, type VI, alpha 3 experimental SAS data
Structure of a collagen VI α3 chain VWA domain array: adaptability and functional implications of myopathy causing mutations Journal of Biological Chemistry 2020 Jul 21 :jbc.RA120.014865
Journal of Biological Chemistry :jbc.RA120.014865 (2020 Jul 21)
Trehalose transferase (TreT) from Thermoproteus uzoniensis - with magnesium and trehalose
Trehalose transferase (Trehalose phosphorylase/synthase) experimental SAS data
Anomeric Selectivity of Trehalose Transferase with Rare L-Sugars ACS Catalysis 2020 Jul 22
ACS Catalysis (2020 Jul 22)
Phosphorylated phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein (amino acids 38-499): pDHPHDEP1
Phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 experimental SAS data
The first DEP domain of the RhoGEF P-Rex1 autoinhibits activity andcontributes to membrane binding. J Biol Chem 2020 Jul 13;
J Biol Chem (2020 Jul 13)
Full-length Plasmodium falciparum Heat shock protein 90 (PfHsp90)
Plasmodium falciparum Heat shock protein 90 experimental SAS data
Solution structure of Plasmodium falciparum Hsp90 indicates a high flexible dimer Archives of Biochemistry and Biophysics 2020 Jul :108468
Archives of Biochemistry and Biophysics :108468 (2020 Jul)
Pentafunctional AROM polypeptide from Chaetomium thermophilum
Pentafunctional AROM polypeptide experimental SAS data
Pentafunctional AROM polypeptide Kratky plot
Architecture and functional dynamics of the pentafunctional AROM complex Nature Chemical Biology 2020 Jul 6
Nature Chemical Biology (2020 Jul 6)

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To cite SASBDB refer to: Kikhney AG, Borges CR, Molodenskiy DS, Jeffries CM, Svergun DI (2020) SASBDB: Towards an automatically curated andvalidated repository for biological scattering data. Protein Science 29(1); 66-75.