Curated repository for small angle scattering data and models


SASBDB currently contains:


940

experimental data sets

1419

models
260 experimental data sets on hold
321 models on hold

Small angle scattering (SAS) of X-ray and neutrons provides structural information on biological macromolecules in solution at a resolution of 1-2 nm.
SASBDB is a fully searchable curated repository of freely accessible and downloadable experimental data, which are deposited together with the relevant experimental conditions, sample details, derived models and their fits to the data.

Recent depositions:

SASDES5 – Neurotrypsin Scavenger Receptor Cysteine-Rich Domain 3 (mmNT-SRCR3) - from SEC-SAXS

Mouse Neurotrypsin Scavenger Receptor Cysteine-Rich Domain 3 experimental SAS data
PDB model
Sample: Mouse Neurotrypsin Scavenger Receptor Cysteine-Rich Domain 3 monomer, 13 kDa Mus musculus protein
Buffer: 25 mM HEPES/NaOH, 0.1 M NaCl, pH: 8
Experiment: SAXS data collected at BM29, ESRF on 2017 May 20
Structural characterization of the third scavenger receptor cysteine-rich domain of murine Neurotrypsin Protein Science (2019)
Canciani A, Catucci G, Forneris F
RgGuinier 1.5 nm
Dmax 4.5 nm
VolumePorod 24 nm3

SASDE88 – Solution structure of phosphoglucosamine mutase (GlmM) from Staphylococcus aureus
Phosphoglucosamine mutase experimental SAS data
DAMFILT model
Inhibition of the Staphylococcus aureus c-di-AMP cyclase DacA by direct interaction with the phosphoglucosamine mutase GlmM.
SASDEK3 – The neutrophil cytosol factor 1 (p47phox) subunit of phagocyte NADPH oxidase
Neutrophil cytosol factor 1 experimental SAS data
CUSTOM IN-HOUSE model
Quantitative live-cell imaging and 3D modeling reveal critical functional features in the cytosolic complex of phagocyte NADPH oxidase.
SASDE24 – Tryparedoxin, in the presence of inhibitor CFT (2-(chloromethyl)-5-(4-fluorophenyl)thieno[2,3-d]pyrimidin-4(3H)-one)
Tryparedoxin experimental SAS data
SASREF MX model
Inhibitor-induced dimerization of an essential oxidoreductase from African Trypanosomes.
SASDDJ6 – SAM-dependent O-Methyltransferase from Mycobacterium hassiacum
Methyltransferase domain protein experimental SAS data
MODELLER model
Biosynthesis of mycobacterial methylmannose polysaccharides requires a unique 1-O-methyltransferase specific for 3-O-methylated mannosides
SASDE96 – Aldehyde dehydrogenase 12 from Zea mays Extrapolated to Infinite Dilution
Aldehyde dehydrogenase 12 experimental SAS data
ALLOSMOD model
Structural and Biochemical Characterization of Aldehyde Dehydrogenase 12, the Last Enzyme of Proline Catabolism in Plants.

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