Curated repository for small angle scattering data and models


SASBDB currently contains:


4308

experimental data sets

5664

models
561 experimental data sets on hold
649 models on hold

Small angle scattering (SAS) of X-ray and neutrons provides structural information on biological macromolecules in solution at a resolution of 1-2 nm.
SASBDB is a fully searchable curated repository of freely accessible and downloadable experimental data, which are deposited together with the relevant experimental conditions, sample details, derived models and their fits to the data.

Recent depositions:

SASDVS5 – Small EDRK-rich factor 1 (SERF1a) bound to HTT-3 peptide

Isoform Short of Small EDRK-rich factor 1HTT3 experimental SAS data
ROSETTA model
Sample: Isoform Short of Small EDRK-rich factor 1 monomer, 7 kDa Homo sapiens protein
HTT3 monomer, 4 kDa synthetic construct protein
Buffer: Sodium phosphate buffer, pH: 7.4
Experiment: SAXS data collected at TPS13A, NSRRC on 2021 May 20
Binding structures of SERF1a with NT17-polyQ peptides of huntingtin exon 1 revealed by SEC-SWAXS, NMR and molecular simulation. IUCrJ (2024)
Lin TC, Shih O, Tsai TY, Yeh YQ, Liao KF, Mansel BW, Shiu YJ, Chang CF, Su AC, Chen YR, Jeng US
RgGuinier 2.3 nm
Dmax 7.2 nm
VolumePorod 9 nm3

Nearly full-length monomeric Human Ubiquitin carboxyl-terminal hydrolase 8 (USP8) (7-1110)
Ubiquitin carboxyl-terminal hydrolase 8 experimental SAS data
Autoinhibition of ubiquitin-specific protease 8: insights into domain interactions and mechanisms of regulation Journal of Biological Chemistry 2024 Aug :107727
Journal of Biological Chemistry :107727 (2024 Aug)
SemDΔAPH bound to Sorting nexin-9, N-terminus - SNX9-SH3
Uncharacterized proteinSorting nexin-9 experimental SAS data
The Chlamydia pneumoniae effector SemD exploits its host’s endocytic machinery by structural and functional mimicry Nature Communications 2024 Aug 24 15(1)
Nature Communications 15(1) (2024 Aug 24)
Homodimeric luciferase EsLuxA
Alkanal monooxygenase alpha chain experimental SAS data
luxA Gene From Enhygromyxa salina Encodes a Functional Homodimeric Luciferase Proteins: Structure, Function, and Bioinformatics 2024 Aug 22
Proteins: Structure, Function, and Bioinformatics (2024 Aug 22)
C-terminal domain of the W protein (CTDw) of Nipah Virus (NiV)
Protein W experimental SAS data
Dissecting Henipavirus W proteins conformational and fibrillation properties: contribution of their N- and C-terminal constituent domains. FEBS J 2024 Aug 23;
FEBS J (2024 Aug 23)
Regulator of telomere elongation helicase 1, HHD-1 domain
Regulator of telomere elongation helicase 1 (Isoform 6, 889-974) experimental SAS data
Structural and biochemical characterization of the C‐terminal region of the human RTEL 1 helicase Protein Science 2024 Aug 24 33(9)
Protein Science 33(9) (2024 Aug 24)

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To cite SASBDB refer to: Kikhney AG, Borges CR, Molodenskiy DS, Jeffries CM, Svergun DI (2020) SASBDB: Towards an automatically curated and validated repository for biological scattering data. Protein Science 29(1); 66-75.