Curated repository for small angle scattering data and models


SASBDB currently contains:


1430

experimental data sets

2261

models
388 experimental data sets on hold
310 models on hold

Small angle scattering (SAS) of X-ray and neutrons provides structural information on biological macromolecules in solution at a resolution of 1-2 nm.
SASBDB is a fully searchable curated repository of freely accessible and downloadable experimental data, which are deposited together with the relevant experimental conditions, sample details, derived models and their fits to the data.

Recent depositions:

SASDG54 – Human macrophage mannose receptor 1 protein

Macrophage mannose receptor 1 experimental SAS data
ITASSER model
Sample: Macrophage mannose receptor 1 dimer, 315 kDa Mouse myeloma cell … protein
Buffer: 50mM Hepes, 100mM NaCl, 1mM DTT, pH: 7
Experiment: SAXS data collected at 12ID-B SAXS/WAXS, Advanced Photon Source (APS), Argonne National Laboratory on 2016 Apr 15
Mannose receptor (CD206) activation in tumor-associated macrophages enhances adaptive and innate antitumor immune responses. Sci Transl Med 12(530) (2020)
Jaynes JM, Sable R, Ronzetti M, Bautista W, Knotts Z, Abisoye-Ogunniyan A, Li D, Calvo R, Dashnyam M, Singh A, Guerin T, White J, Ravichandran S, Kumar P, Talsania K, Chen V, Ghebremedhin A, Karanam B, Bin Salam A, Amin R, Odzorig T, Aiken T, Nguyen V, Bian Y, Zarif JC, de Groot AE, Mehta M, Fan L, Hu X, Simeonov A, Pate N, Abu-Asab M, Ferrer M, Southall N, Ock CY, Zhao Y, Lopez H, Kozlov S, de Val N, Yates CC, Baljinnyam B, Marugan J, Rudloff U
RgGuinier 7.9 nm
Dmax 30.1 nm
VolumePorod 584 nm3

SASDHF4 – Lipoprotein lipase-GPIHBP1-monoclonal antibody (5D2) complex
Lipoprotein lipaseGlycosylphosphatidylinositol-anchored high density lipoprotein-binding protein 1Monoclonal Antibody Fragment 5D2 experimental SAS data
CORAL model
Unfolding of monomeric lipoprotein lipase by ANGPTL4: Insight into the regulation of plasma triglyceride metabolism
SASDF29 – Double-stranded RNA-binding protein Staufen homolog 1 - RNA binding domain 4 - in complex with STAU1 binding site within the ADP-ribosylation factor1
Double-stranded RNA-binding protein Staufen homolog 1 - RNA binding domain 4ADP-ribosylation factor1 - short experimental SAS data
OTHER model
Staufen1 reads out structure and sequence features in ARF1 dsRNA for target recognition.
SASDF87 – Mosqutio-larvicidal Binary (BinAB) toxin Receptor Cqm1 protein in 100% D2O
Binary toxin receptor Cqm1 protein experimental SAS data
PDB model
Small-angle neutron scattering studies suggest the mechanism of BinAB protein internalization
SASDF95 – Pseudomonas aeruginosa antitoxin HigA bound to duplex DNA: PaHigA-DNA complex
Uncharacterized proteinDNA Duplex experimental SAS data
PDB model
Structural Insights Into the Transcriptional Regulation of HigBA Toxin–Antitoxin System by Antitoxin HigA in Pseudomonas aeruginosa
SASDHX3 – Hyperstable de novo protein Super WA20 (SUWA)
Hyperstable de novo protein Super WA20 experimental SAS data
PDB model
Hyperstable De Novo Protein with a Dimeric Bisecting Topology.

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