Curated repository for small angle scattering data and models


SASBDB currently contains:


969

experimental data sets

1448

models
262 experimental data sets on hold
318 models on hold

Small angle scattering (SAS) of X-ray and neutrons provides structural information on biological macromolecules in solution at a resolution of 1-2 nm.
SASBDB is a fully searchable curated repository of freely accessible and downloadable experimental data, which are deposited together with the relevant experimental conditions, sample details, derived models and their fits to the data.

Recent depositions:

SASDDH8 – Integrin beta4, fragment of the cytoplasmic region that includes the final part of the connecting segment and the third and fourth FnIII domains (FnIII-3,4). Point mutant A1468R

Integrin beta-4 (1436-1666) A1468R experimental SAS data
Integrin beta4, fragment of the cytoplasmic region that includes the final part of the connecting segment and the third and fourth FnIII domains (FnIII-3,4). Point mutant A1468R Rg histogram
Sample: Integrin beta-4 (1436-1666) A1468R monomer, 26 kDa Homo sapiens protein
Buffer: 20 mM Sodium Phosphate 150 mM NaCl 5% glycerol 3 mM DTT, pH: 7.5
Experiment: SAXS data collected at EMBL P12, PETRA III on 2013 Nov 26
Integrin α6β4 recognition of a linear motif of bullous pemphigoid antigen BP230 controls its recruitment to hemidesmosomes: Supplemental figures S1 to S10 and table S1 (2018)
Manso J, Gómez-Hernández M, Carabias A, Alonso-García N, García-Rubio I, Kreft M, Sonnenberg A, de Pereda J
RgGuinier 2.8 nm
Dmax 10.9 nm
VolumePorod 35 nm3

SASDDQ4 – LIM/homeobox protein Lhx4 LIM domains fused to the LIM interaction domain (LID) of Insulin gene enhancer protein ISL-2
LIM/homeobox protein Lhx4Insulin gene enhancer protein ISL-2 experimental SAS data
DAMMIN model
Mutation in a flexible linker modulates binding affinity for modular complexes.
SASDD33 – Toxin/Antitoxin complex from M. tuberculosis
Mycobacterial cidal toxinMycobacterial cidal antitoxin experimental SAS data
PDB model
An NAD+ Phosphorylase Toxin Triggers Mycobacterium tuberculosis Cell Death.
SASDDG5 – Mammalian prion protein mRNA (PrP mRNA wild type)
octo-repeat PrP mRNA experimental SAS data
DAMFILT model
Octa-repeat domain of the mammalian prion protein mRNA forms stable A-helical hairpin structure rather than G-quadruplexes.
SASDES5 – Neurotrypsin Scavenger Receptor Cysteine-Rich Domain 3 (mmNT-SRCR3) - from SEC-SAXS
Mouse Neurotrypsin Scavenger Receptor Cysteine-Rich Domain 3 experimental SAS data
PDB model
Structural characterization of the third scavenger receptor cysteine-rich domain of murine Neurotrypsin
SASDE88 – Solution structure of phosphoglucosamine mutase (GlmM) from Staphylococcus aureus
Phosphoglucosamine mutase experimental SAS data
DAMFILT model
Inhibition of the Staphylococcus aureus c-di-AMP cyclase DacA by direct interaction with the phosphoglucosamine mutase GlmM.

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