Curated repository for small angle scattering data and models


SASBDB currently contains:


4657

experimental data sets

5865

models
602 experimental data sets on hold
790 models on hold

Small angle scattering (SAS) of X-ray and neutrons provides structural information on biological macromolecules in solution at a resolution of 1-2 nm.
SASBDB is a fully searchable curated repository of freely accessible and downloadable experimental data, which are deposited together with the relevant experimental conditions, sample details, derived models and their fits to the data.

Recent depositions:

SASDW97 – Recombination directionality factor (6H-RdfS) from M.japonicum bound to 40mer DNA

Recombination directionality factor RdfSattP_8 40-mer DNA experimental SAS data
OTHER model
Sample: Recombination directionality factor RdfS tetramer, 52 kDa Mesorhizobium japonicum R7A protein
AttP_8 40-mer DNA dimer, 25 kDa DNA
Buffer: 150 mM Tris-HCl, 300 mM NaCl, 5% v/v glycerol, pH: 7.4
Experiment: SAXS data collected at SAXS/WAXS, Australian Synchrotron on 2019 Jun 19
Structural basis for control of integrative and conjugative element excision and transfer by the oligomeric winged helix–turn–helix protein RdfS Nucleic Acids Research 53(6) (2025)
Verdonk C, Agostino M, Eto K, Hall D, Bond C, Ramsay J
RgGuinier 3.8 nm
Dmax 13.8 nm
VolumePorod 134 nm3

Marchantia polymorpha Auxin Response Factor 3 in complex with high affinity DNA
Auxin response factorHigh Affinity ARF binding sequence inverted repeat with 6 nucleotide spacing experimental SAS data
The structure and function of the DNA binding domain of class B MpARF2 share more traits with class A AtARF5 than to that of class B AtARF1. Structure 2025 Mar 7;
Structure (2025 Mar 7)
Human DNA methyltransferase 3 beta DNMT3B (413-853) and DNA methyltransferase 3-like DNMT3L (178-379) in complex with histone H3
Histone H3.3DNA methyltransferase 3-like (178-379)DNA methyltransferase 3 beta (413-853) experimental SAS data
Histone modification-driven structural remodeling unleashes DNMT3B in DNA methylation. Sci Adv 2025 Mar 28;11(13):eadu8116
Sci Adv 11(13):eadu8116 (2025 Mar 28)
RNA Device 43 in ligand-bound state (holo-D43)
RNA Device 43 in ligand-bound state experimental SAS data
Structural investigation of an RNA device that regulates PD-1 expression in mammalian cells. Nucleic Acids Res 2025 Feb 27;53(5)
Nucleic Acids Res 53(5) (2025 Feb 27)
Trypanosoma brucei ESAG4 membrane-proximal Venus Fly Trap domain 2 (VFT2)
adenylate cyclase experimental SAS data
Biophysical analysis of the membrane-proximal Venus Flytrap domain of ESAG4 receptor-like adenylate cyclase from Trypanosoma brucei. Mol Biochem Parasitol 2024 Dec;260:111653
Mol Biochem Parasitol 260:111653 (2024 Dec)
Immunoglobulin light chain AL55
Immunoglobulin light chain AL55 experimental SAS data
A conformational fingerprint for amyloidogenic light chains eLife 2025 Mar 03 13
eLife 13 (2025 Mar 03)

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To cite SASBDB refer to: Kikhney AG, Borges CR, Molodenskiy DS, Jeffries CM, Svergun DI (2020) SASBDB: Towards an automatically curated and validated repository for biological scattering data. Protein Science 29(1); 66-75.