Curated repository for small angle scattering data and models


SASBDB currently contains:


870

experimental data sets

1322

models
240 experimental data sets on hold
297 models on hold

Small angle scattering (SAS) of X-ray and neutrons provides structural information on biological macromolecules in solution at a resolution of 1-2 nm.
SASBDB is a fully searchable curated repository of freely accessible and downloadable experimental data, which are deposited together with the relevant experimental conditions, sample details, derived models and their fits to the data.

Recent depositions:

SASDE35 – Ovalbumin monomer from in-house SEC-SAXS

Ovalbumin experimental SAS data
PDB model
Sample: Ovalbumin monomer, 43 kDa Gallus gallus protein
Buffer: PBS, pH: 7.4
Experiment: SAXS data collected at Xenocs BioXolver L, Copenhagen University, Department of Drug Design and Pharmacology on 2018 Jan 24
Size-exclusion chromatography small-angle X-ray scattering of water soluble proteins on a laboratory instrument Journal of Applied Crystallography 51(6) (2018)
Bucciarelli S, Midtgaard S, Nors Pedersen M, Skou S, Arleth L, Vestergaard B
RgGuinier 2.4 nm
Dmax 7.8 nm
VolumePorod 55 nm3

SASDEQ7 – Filamin A Ig-like domains 3-5 (FLNa3-5)
Filamin A Ig-like domains 3-5 experimental SAS data
PDB model
Non-syndromic Mitral Valve Dysplasia Mutation Changes the Force Resilience and Interaction of Human Filamin A.
SASDEN4 – Protein tyrosine phosphatase SHP2
Tyrosine-protein phosphatase non-receptor type 11 experimental SAS data
ALLOSMOD model
Mechanism of activating mutations and allosteric drug inhibition of the phosphatase SHP2
SASDD76 – Phox Homologue (PX) - C2 domains of human phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha (PI3KC2α) in complex with inositol-hexaphosphate (IP6)
Phox Homology (PX) - C2 domains of human Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha experimental SAS data
DAMFILT model
Molecular Basis for Membrane Recruitment by the PX and C2 Domains of Class II Phosphoinositide 3-Kinase-C2α.
SASDDM6 – Calbindin-D28K
Calbindin experimental SAS data
DAMMIF model
The X-ray structure of human calbindin-D28K: an improved model
SASDDG9 – The 2:1 complex of Synechocystis disulphide-trapped Fluorescence recovery protein dimer (CC mutant) and orange carotenoid-binding protein-ΔNTE (orange form)
Fluorescence recovery proteinOrange carotenoid-binding protein experimental SAS data
GASBOR model
OCP-FRP protein complex topologies suggest a mechanism for controlling high light tolerance in cyanobacteria.

Browse the contents according to:

Organism
Macromolecule type
Model type
Dissemination type