Curated repository for small angle scattering data and models


SASBDB currently contains:


2730

experimental data sets

3850

models
501 experimental data sets on hold
603 models on hold

Small angle scattering (SAS) of X-ray and neutrons provides structural information on biological macromolecules in solution at a resolution of 1-2 nm.
SASBDB is a fully searchable curated repository of freely accessible and downloadable experimental data, which are deposited together with the relevant experimental conditions, sample details, derived models and their fits to the data.

Recent depositions:

SASDNK7 – Guanine-rich DNA derived from the promoter region of c-MYC gene (MYC22-G14T/G23T) with KCl

MYC22-G14T/G23T experimental SAS data
PDB (PROTEIN DATA BANK) model
Sample: MYC22-G14T/G23T monomer, 7 kDa Homo sapiens DNA
Buffer: 50 mM Tris, 30 mM KCl, pH: 8
Experiment: SAXS data collected at BL-10C, Photon Factory (PF), High Energy Accelerator Research Organization (KEK) on 2022 Feb 27
Small-angle X-ray scattering data of a guanine-rich DNA derived from the promoter region of c-MYC gene in solution Data in Brief :108285 (2022)
Miyauchi K, Imamura H, Yamaoki Y, Kato M
RgGuinier 1.3 nm
Dmax 5.3 nm
VolumePorod 9 nm3

Human ganglioside-induced differentiation-associated protein 1 (GDAP1) missense mutant H123R, construct GDAP1∆302-358
Ganglioside-induced differentiation-associated protein 1 (H123R) experimental SAS data
Structural insights into Charcot-Marie-Tooth disease-linked mutations in human GDAP1. FEBS Open Bio 2022 May 4;
FEBS Open Bio (2022 May 4)
Human apo Nocturnin - Deletion construct (Δ107-120) - Extended
Nocturnin - Deletion construct - Δ107-120 experimental SAS data
The Disordered Amino Terminus of the Circadian Enzyme Nocturnin Modulates Its NADP(H) Phosphatase Activity by Changing Protein Dynamics. Biochemistry 2022 May 10;
Biochemistry (2022 May 10)
The Fe–S cluster assembly 1 homolog of pigeon (Elution No.300)
Iron-sulfur cluster assembly 1 homolog, mitochondrial experimental SAS data
Magnetic field effects on the structure and molecular behavior of pigeon iron–sulfur protein Protein Science 2022 May 09 31(6)
Protein Science 31(6) (2022 May 09)
DNA-binding protein from starved cells: DgrDpsWT in 50 mM MOPS, 480 mM NaCl pH 7.0
DNA protection during starvation, DPS (Ferritin superfamily) experimental SAS data
The Conformation of the N-Terminal Tails of Deinococcus grandis Dps Is Modulated by the Ionic Strength International Journal of Molecular Sciences 2022 Apr 28 23(9):4871
International Journal of Molecular Sciences 23(9):4871 (2022 Apr 28)
Aquifex aeolicus McoA metaloxidase evolved variant (2F4)
McoA evolved variant 2F4 (Periplasmic cell division protein (SufI)) experimental SAS data
Distal Mutations Shape Substrate-Binding Sites during Evolution of a Metallo-Oxidase into a Laccase ACS Catalysis 2022 Apr 13 :5022-5035
ACS Catalysis :5022-5035 (2022 Apr 13)

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To cite SASBDB refer to: Kikhney AG, Borges CR, Molodenskiy DS, Jeffries CM, Svergun DI (2020) SASBDB: Towards an automatically curated and validated repository for biological scattering data. Protein Science 29(1); 66-75.