Curated repository for small angle scattering data and models


SASBDB currently contains:


1483

experimental data sets

2298

models
430 experimental data sets on hold
384 models on hold

Small angle scattering (SAS) of X-ray and neutrons provides structural information on biological macromolecules in solution at a resolution of 1-2 nm.
SASBDB is a fully searchable curated repository of freely accessible and downloadable experimental data, which are deposited together with the relevant experimental conditions, sample details, derived models and their fits to the data.

Recent depositions:

SASDEW3 – DNA ligase A (MtbLigA) complexed with exodeoxyribonuclease III protein (MtbXthA)

DNA ligase AProbable exodeoxyribonuclease III protein XthA experimental SAS data
DAMMIF model
Sample: DNA ligase A monomer, 76 kDa Mycobacterium tuberculosis (strain … protein
Probable exodeoxyribonuclease III protein XthA monomer, 33 kDa Mycobacterium tuberculosis protein
Buffer: 50 mM Tris-HCl, 200 mM NaCl, 2 mM β-mercaptoethanol, pH: 8
Experiment: SAXS data collected at BM29, ESRF on 2017 May 13
M. tuberculosis class II apurinic/ apyrimidinic-endonuclease/3'-5' exonuclease (XthA) engages with NAD+-dependent DNA ligase A (LigA) to counter futile cleavage and ligation cycles in base excision repair. Nucleic Acids Res (2020)
Khanam T, Afsar M, Shukla A, Alam F, Kumar S, Soyar H, Dolma K, Pasupuleti M, Srivastava KK, Ampapathi RS, Ramachandran R
RgGuinier 6.2 nm
Dmax 23.9 nm
VolumePorod 662 nm3

SASDF42 – Human serum albumin in complex with somapacitan
Human serum albuminsomapacitan experimental SAS data
SASREF model
Identification of binding sites on human serum albumin for somapacitan - a long-acting growth hormone derivative.
SASDHS4 – Protein ninH from Bacteriophage lambda (N-terminal histidine tagged) T15A mutated
Protein ninH experimental SAS data
MODELLER model
A bacteriophage mimic of the bacterial nucleoid-associated protein Fis.
SASDHS5 – Full-length Mouse TIFA dimer
TRAF-interacting protein with FHA domain-containing protein A experimental SAS data
DAMFILT model
Structural analysis of TIFA: Insight into TIFA-dependent signal transduction in innate immunity.
SASDFE5 – Tetracycline repressor (class D), TetR(D), in complex with 5a,6-anhydrotetracycline (ATc)
Tetracycline repressor (class D)5a,6-anhydrotetracycline experimental SAS data
PDB model
Thermodynamics, cooperativity and stability of the tetracycline repressor (TetR) upon tetracycline binding.
SASDGA5 – The C-terminal cell-surface signaling domain of the Pseudomonas capeferrum anti-sigma regulator PupR
PupR protein experimental SAS data
MULTIFOXS model
Structural basis of cell surface signaling by a conserved sigma regulator in Gram-negative bacteria.

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