SASDB65 – Tyrosine-protein phosphatase (YopH)/putative yopH targeting protein (SycH) heterotrimeric complex

SycH putative yopH targeting proteinTyrosine-protein phosphatase YopH experimental SAS data
CRYSOL model
Sample: SycH putative yopH targeting protein dimer, Yersinia pseudotuberculosis protein
Tyrosine-protein phosphatase YopH monomer, Yersinia pseudotuberculosis protein
Buffer: 50 mM HEPES 2mM TCEP, pH: 6.8
Experiment: SAXS data collected at P12, PETRA III 2016-Aug-01
Use of SAXS to study the structure of the complex formed between dimeric Sych and YopH protein
Alessandro Spilotros
RgGuinier 3.0 nm
Dmax 12.5 nm
VolumePorod 89 nm3

SASDC63 – Fowlpox Virus FPV039 antiapoptotic Bcl-2 viral protein in complex with BaK BH3 peptide (FPV039:BAK)

Bcl-2-like protein FPV039Uncharacterized protein (BAK1) experimental SAS data
Bcl-2-like protein FPV039 Uncharacterized protein (BAK1) Kratky plot
Sample: Bcl-2-like protein FPV039 monomer, Fowlpox virus (strain ... protein
Uncharacterized protein (BAK1) monomer, Gallus gallus protein
Buffer: 20 mM trisodium citrate pH, 200 mM NaCl, pH: 6
Experiment: SAXS data collected at SAXS/WAXS, Australian Synchrotron 2015-Oct-02
Structural Basis of Apoptosis Inhibition by the Fowlpox Virus Protein FPV039. J Biol Chem 2017 Apr 14;
Anasir MI, Caria S, Skinner MA, Kvansakul M
RgGuinier 2.0 nm

SASDBE7 – ESX-5 type VII secretion system protein EccC5

ESX-5 type VII secretion system protein EccC5 experimental SAS data
ESX-5 type VII secretion system protein EccC5 Rg histogram
Sample: ESX-5 type VII secretion system protein EccC5 monomer, Mycobacterium xenopi RIVM700367 protein
Buffer: 20 mM Tris 200 mM NaCl 5%(v/v) Glycerol, pH: 8
Experiment: SAXS data collected at P12, PETRA III 2016-Jul-15
Structure of the mycobacterial ESX-5 type VII secretion system membrane complex by single-particle analysis Nature Microbiology 2017 Apr 10 2:17047
Beckham K, Ciccarelli L, Bunduc C, Mertens H, Ummels R, Lugmayr W, Mayr J, Rettel M, Savitski M, Svergun D, Bitter W, Wilmanns M, Marlovits T, Parret A, Houben E
RgGuinier 6.2 nm
Dmax 23.0 nm
VolumePorod 255 nm3

SASDBA9 – E. coli CcdB2-CcdA2-CcdB2 toxin/antitoxin heterohexamer complex

Toxin CcdBAntitoxin CcdAToxin CcdB experimental SAS data
CRYSOL model
Sample: Toxin CcdB dimer, Escherichia coli (strain ... protein
Antitoxin CcdA dimer, Escherichia coli (strain ... protein
Toxin CcdB dimer, Escherichia coli (strain ... protein
Buffer: 10 mM Tris 50 mM NaCl, pH: 7.3
Experiment: SAXS data collected at SWING, SOLEIL 2013-Jul-24
Molecular mechanism governing ratio-dependent transcription regulation in the ccdAB operon Nucleic Acids Research 2017 Apr 7 45(6):2937-2950
Vandervelde A, Drobnak I, Hadži S, Sterckx Y, Welte T, De Greve H, Charlier D, Efremov R, Loris R, Lah J
RgGuinier 3.4 nm
Dmax 12.0 nm
VolumePorod 92 nm3

SASDB99 – Extracellular assembly of the human TSLP:TSLPR:IL-7Ralpha complex

Thymic stromal lymphopoietinInterleukin-7 receptor subunit alphaCytokine receptor-like factor 2 experimental SAS data
ALLOSMOD-FOXS model
Sample: Thymic stromal lymphopoietin monomer, Homo sapiens protein
Interleukin-7 receptor subunit alpha monomer, Homo sapiens protein
Cytokine receptor-like factor 2 monomer, Homo sapiens protein
Buffer: 10 mM Hepes, 150 mM NaCl, pH: 7.4
Experiment: SAXS data collected at SWING, SOLEIL 2016-Apr-08
Structure and antagonism of the receptor complex mediated by human TSLP in allergy and asthma. Nat Commun 2017 Apr 3;8:14937
Verstraete K, Peelman F, Braun H, Lopez J, Van Rompaey D, Dansercoer A, Vandenberghe I, Pauwels K, Tavernier J, Lambrecht BN, Hammad H, De Winter H, Beyaert R, Lippens G, Savvides SN
RgGuinier 3.1 nm
Dmax 10.3 nm
VolumePorod 98 nm3

344 hits found.