Browse by MACROMOLECULE type: protein

SASDU85 – Wild-type phosphoserine phosphatase RsbU dimer

Phosphoserine phosphatase RsbU experimental SAS data
MULTIFOXS model
Sample: Phosphoserine phosphatase RsbU dimer, 77 kDa Bacillus subtilis (strain … protein
Buffer: 20 mM HEPES, 100 mM NaCl, 5 mM DTT, pH: 7.5
Experiment: SAXS data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2023 Feb 24
A general mechanism for initiating the bacterial general stress response. Elife 13 (2025)
Baral R, Ho K, Kumar RP, Hopkins JB, Watkins MB, LaRussa S, Caban-Penix S, Calderone LA, Bradshaw N
RgGuinier 3.9 nm
Dmax 14.3 nm
VolumePorod 117 nm3

SASDU95 – Hyperactive variant of phosphoserine phosphatase RsbU (Q94L) bound to the activator serine/threonine-protein kinase RsbT (heterotetrameric complex)

Serine/threonine-protein kinase RsbTPhosphoserine phosphatase RsbU (Q94L) experimental SAS data
Serine/threonine-protein kinase RsbT Phosphoserine phosphatase RsbU (Q94L) Kratky plot
Sample: Serine/threonine-protein kinase RsbT dimer, 29 kDa Bacillus subtilis (strain … protein
Phosphoserine phosphatase RsbU (Q94L) dimer, 77 kDa Bacillus subtilis (strain … protein
Buffer: 20 mM HEPES, 100 mM NaCl, 5 mM DTT, pH: 7.5
Experiment: SAXS data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2023 Feb 24
A general mechanism for initiating the bacterial general stress response. Elife 13 (2025)
Baral R, Ho K, Kumar RP, Hopkins JB, Watkins MB, LaRussa S, Caban-Penix S, Calderone LA, Bradshaw N
RgGuinier 3.5 nm
Dmax 12.3 nm
VolumePorod 119 nm3

SASDVY6 – Wild-type full-length Mitochondrial intermembrane space import and assembly protein 40 (CHCHD4)

Mitochondrial intermembrane space import and assembly protein 40 experimental SAS data
Mitochondrial intermembrane space import and assembly protein 40 Kratky plot
Sample: Mitochondrial intermembrane space import and assembly protein 40 monomer, 16 kDa Homo sapiens protein
Buffer: 25 mM HEPES, 150 mM NaCl, 2 mM TCEP, pH: 7.5
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2021 Oct 26
NADH-bound AIF activates the mitochondrial CHCHD4/MIA40 chaperone by a substrate-mimicry mechanism. EMBO J (2025)
Brosey CA, Shen R, Tainer JA
RgGuinier 2.9 nm
Dmax 9.2 nm
VolumePorod 56 nm3

SASDVZ6 – Mitochondrial intermembrane space import and assembly protein 40 (CHCHD4) triple mutant I12A/F14A/H20A (AIA-A)

Mitochondrial intermembrane space import and assembly protein 40 experimental SAS data
Mitochondrial intermembrane space import and assembly protein 40 Kratky plot
Sample: Mitochondrial intermembrane space import and assembly protein 40 monomer, 16 kDa Homo sapiens protein
Buffer: 25 mM HEPES, 150 mM NaCl, 2 mM TCEP, pH: 7.5
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2021 Oct 26
NADH-bound AIF activates the mitochondrial CHCHD4/MIA40 chaperone by a substrate-mimicry mechanism. EMBO J (2025)
Brosey CA, Shen R, Tainer JA
RgGuinier 3.1 nm
Dmax 10.5 nm
VolumePorod 62 nm3

SASDV27 – Mitochondrial intermembrane space import and assembly protein 40 (CHCHD4) point mutant H20D

Mitochondrial intermembrane space import and assembly protein 40 experimental SAS data
Mitochondrial intermembrane space import and assembly protein 40 Kratky plot
Sample: Mitochondrial intermembrane space import and assembly protein 40 monomer, 16 kDa Homo sapiens protein
Buffer: 25 mM HEPES, 150 mM NaCl, 2 mM TCEP, pH: 7.5
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2021 Oct 26
NADH-bound AIF activates the mitochondrial CHCHD4/MIA40 chaperone by a substrate-mimicry mechanism. EMBO J (2025)
Brosey CA, Shen R, Tainer JA
RgGuinier 3.2 nm
Dmax 11.2 nm
VolumePorod 66 nm3

SASDV37 – Mitochondrial intermembrane space import and assembly protein 40 (CHCHD4) point mutant L28D

Mitochondrial intermembrane space import and assembly protein 40 experimental SAS data
Mitochondrial intermembrane space import and assembly protein 40 Kratky plot
Sample: Mitochondrial intermembrane space import and assembly protein 40 monomer, 16 kDa Homo sapiens protein
Buffer: 25 mM HEPES, 150 mM NaCl, 2 mM TCEP, pH: 7.5
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2021 Oct 26
NADH-bound AIF activates the mitochondrial CHCHD4/MIA40 chaperone by a substrate-mimicry mechanism. EMBO J (2025)
Brosey CA, Shen R, Tainer JA
RgGuinier 2.8 nm
Dmax 9.2 nm
VolumePorod 52 nm3

SASDV47 – Peptide-linked fusion protein of Apoptosis-inducing factor 1 AIF(104-613) point mutant W196A and the N-terminal segment of Mitochondrial intermembrane space import and assembly protein 40 CHCHD4(1-45)

Mitochondrial intermembrane space import and assembly protein 40Apoptosis-inducing factor 1, mitochondrial experimental SAS data
Mitochondrial intermembrane space import and assembly protein 40 Apoptosis-inducing factor 1, mitochondrial Kratky plot
Sample: Mitochondrial intermembrane space import and assembly protein 40 dimer, 12 kDa Homo sapiens protein
Apoptosis-inducing factor 1, mitochondrial dimer, 113 kDa Homo sapiens protein
Buffer: 25 mM HEPES, 150 mM NaCl, 2 mM TCEP, pH: 7.5
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2018 Nov 28
NADH-bound AIF activates the mitochondrial CHCHD4/MIA40 chaperone by a substrate-mimicry mechanism. EMBO J (2025)
Brosey CA, Shen R, Tainer JA
RgGuinier 3.9 nm
Dmax 12.9 nm
VolumePorod 289 nm3

SASDSK2 – SEC-SAXS data of wild-type estrogen receptor alpha, N-terminal domain (NTD) at pH 7.4

Estrogen receptor experimental SAS data
Estrogen receptor Kratky plot
Sample: Estrogen receptor monomer, 20 kDa Homo sapiens protein
Buffer: 20 mM sodium phosphate, 150 mM NaCl, 0.5 mM EDTA, 0.1 mM PMSF, pH: 7.4
Experiment: SAXS data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2019 Jul 21
The sequence–structure–function relationship of intrinsic ERα disorder Nature (2025)
Du Z, Wang H, Luo S, Yun Z, Wu C, Yang W, Buck M, Zheng W, Hansen A, Kao H, Yang S
RgGuinier 3.2 nm
Dmax 14.0 nm
VolumePorod 47 nm3

SASDSE5 – SEC-SAXS data of mutant estrogen receptor alpha (S118A), N-terminal domain (NTD) at pH 7.4

Estrogen receptor (mutant S118A) experimental SAS data
Estrogen receptor (mutant S118A) Kratky plot
Sample: Estrogen receptor (mutant S118A) monomer, 20 kDa Homo sapiens protein
Buffer: 20 mM sodium phosphate, 150 mM NaCl, 0.5 mM EDTA, 0.1 mM PMSF, pH: 7.4
Experiment: SAXS data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2019 Jul 21
The sequence–structure–function relationship of intrinsic ERα disorder Nature (2025)
Du Z, Wang H, Luo S, Yun Z, Wu C, Yang W, Buck M, Zheng W, Hansen A, Kao H, Yang S
RgGuinier 3.2 nm
Dmax 15.0 nm
VolumePorod 71 nm3

SASDSF5 – SEC-SAXS data of mutant estrogen receptor alpha (S118D), N-terminal domain (NTD) at pH 7.4

Estrogen receptor (mutant S118D) experimental SAS data
Estrogen receptor (mutant S118D) Kratky plot
Sample: Estrogen receptor (mutant S118D) monomer, 20 kDa Homo sapiens protein
Buffer: 20 mM sodium phosphate, 150 mM NaCl, 0.5 mM EDTA, 0.1 mM PMSF, pH: 7.4
Experiment: SAXS data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2019 Jul 21
The sequence–structure–function relationship of intrinsic ERα disorder Nature (2025)
Du Z, Wang H, Luo S, Yun Z, Wu C, Yang W, Buck M, Zheng W, Hansen A, Kao H, Yang S
RgGuinier 3.5 nm
Dmax 16.0 nm
VolumePorod 62 nm3