Tel50 + ligands (BR19)

valeria libera.

SASDZG4 – human telomeric g-quadruplex Tel50+BRACO-19 (1:3)

human telomeric g-quadruplex
MWexperimental 16 kDa
MWexpected 8 kDa
log I(s) 2.86×10-2 2.86×10-3 2.86×10-4 2.86×10-5
human telomeric g-quadruplex small angle scattering data  s, nm-1
ln I(s)
human telomeric g-quadruplex Guinier plot ln 2.87×10-2 Rg: 2.0 nm 0 (2.0 nm)-2 s2
(sRg)2I(s)/I(0)
human telomeric g-quadruplex Kratky plot 1.104 0 √3 sRg

Data validation

There are no models related to this curve.

Synchrotron SAXS data from solutions of human telomeric g-quadruplex Tel50+BRACO-19 (1:3) in 5 mM KH2PO4/K2HPO4, pH 7 were collected on the BM29 beam line at the ESRF storage ring (Grenoble, France) using a Pilatus 1M detector at a sample-detector distance of 2.8 m and at a wavelength of λ = 0.099 nm (I(s) vs s, where s = 4πsinθ/λ, and 2θ is the scattering angle). One solute concentration of 0.80 mg/ml was measured at 20°C. 10 successive 1 second frames were collected. The data were normalized to the intensity of the transmitted beam and radially averaged; the scattering of the solvent-blank was subtracted.

human telomeric g-quadruplex (Tel26)
Mol. type   DNA
Olig. state   Monomer
Mon. MW   8.2 kDa
Sequence   FASTA