Rhoptry kinase family protein

BPK1 protein

Organism: Toxoplasma gondii (strain ATCC 50853 / GT1)

Monomeric molecular weight: 35.8 kDa

Oligomeric state: Tetramer

Total molecular weight: 143.0 kDa

UniProt: S7UMR4 (61-377)

Sequence:

SVYRIPLADMTFWSWMSYLKELPDIDESRNPILK RLLSGSFLRRDGSTTVNVRVPARELVRLLSLTPEQQREGVSAKVRLINL LDPKYSVYEPYLYREILPKRSPLLLPSLGEYRGAFLTYIFHPLSKGLVGD MLETGRSHPDVQVLAANMVAALKSLHNLGLLHRSIELNSFSVLPDGT VVLGGLDTAAPIGTETRLWVGFFGQETAPEIDRNFLADLALTQGRHTV KSDVYSLGVAFRNLVQLLGNGNIGPEDRGAVRQDHLELLDKLSQKMIE EEPGNRPTIEEIMKDPLFEGLNFEDIEEGKARPFRYKQNRL

BPK1 is protein secreted by apicomplexan parasite Toxoplasma gondii from its dense granules, when it has infected the host cell. The BPK1 is a part of the cyst wall in the bradyzoite stage of Toxoplasma. It binds to other proteins and maintains the integrity of the bradyzoite cyst wall.