AH receptor-interacting protein (R9Q)

(HIS)6-AIP protein

Organism: Homo sapiens

Monomeric molecular weight: 39.0 kDa

Oligomeric state: Monomer

Total molecular weight: 39.0 kDa

UniProt: O00170 (2-330)

Sequence:

MHHHHHHVIEGRADIIARLQEDGIQKRVIQEGRGELPDFQDGTKATFHYRTLHSDDEGTVLDDSRARGKPMELIIGKKFKLPVWETIVCTMREGEIAQFLCDIKHVVLYPLVAKSLRNIAVGKDPLEGQRHCCGVAQMREHSSLGHADLDALQQNPQPLIFHMEMLKVESPGTYQQDPWAMTDEEKAKAVPLIHQEGNRLYREGHVKEAAAKYYDAIACLKNLQMKEQPGSPEWIQLDKQITPLLLNYCQCKLVVEEYYEVLDHCSSILNKYDDNVKAYFKRGKAHAAVWNAQEAQADFAKVLELDPALAPVVSRELRALEARIRQKDEEDKARFRGIFSH

(AIP) is a cytoplasmic molecular co-chaperone and tumour suppressor that assists in protein stability and complex formation involving the aryl hydrocarbon receptor. The protein construct used for SAXS contains an additional N-terminal polyhistidine tag (MHHHHHHVIEGR) and contains a R9Q point mutation.