Pentraxin-related protein PTX3 (N-terminal deletion mutant)

Δ1-24 PTX3 protein
Organism: Homo sapiens
Monomeric molecular weight: 37.6 kDa
Oligomeric state: Octamer
Total molecular weight: 300.7 kDa
UniProt: P26022 (42-381)
Sequence:

Δ1-24 PTX3 was expressed in human embryonic kidney (HEK) Expi293F cells and is therefore glycosylated. The amino acid numbering of the deletion mutant (Δ1-24) refers to the amino acid numbering of the mature protein, i.e., after the signal sequence has been cleaved (and therefore this construct corresponds to the removal of amino acids 1-17 (signal sequence) and 18-41 (Δ1-24) from the UniProt P26022 reference sequence). A48 isoform. The protein construct used for SAXS also contains and additional two non-native amino acids at the N-terminus (EL).