Pentraxin-related protein PTX3 (C317S, C318S)

Half-PTX3 protein

Organism: Homo sapiens

Monomeric molecular weight: 40.1 kDa

Oligomeric state: Tetramer

Total molecular weight: 160.4 kDa

UniProt: P26022 (18-381)

Sequence:

ENSDDYDLMYVNLDNEIDNGLHPTEDPTPCACGQEHSEWDKLFIMLENSQMRERMLLQATDDVLRGELQR LREELGRLAESLARPCAPGAPAEARLTSALDELLQATRDAGRRLARMEGAEAQRPEEAGRALAAVLEELRQTRADLHAVQGWAARSWLPAGCETAILFPMRSKKIFGSVHPVRPMRLESFSACIWVKATDVLNKTILFSYGTKRNPYEIQLYLSYQSIVFVVGGEENKLVAEAMVSLGRWTHLCGTWNSEEGLTSLWVNGELAATTVEMATGHIVPEGGILQIGQEKNGSSVGGGFDETLAFSGRLTGFNIWDSVLSNEEIRETGGAESCHIRGNIVGWGVTEIQPHGGAQYVS

Half-PTX3 was expressed in human embryonic kidney (HEK) Expi293F cells and is therefore glycosylated. Signal sequence cleaved (amino acids 1-17 of UniProt P26022). A48 isoform. Amino acids C317 and C318 mutated to serine.