Venom Allergen-like protein 11

SmVAL11 protein

Organism: Schistosoma mansoni

Monomeric molecular weight: 47 kDa

Oligomeric state: Other

Total molecular weight: 47 kDa

UniProt: Q1WL54 (1-423)

Sequence:

MSRLDDFREDCFRAHNEKRLLHGVCALRHSLALDKTAQDWAEALLSEDGIKNSPLSSRGEVGESISVRTSTGTHVDMQGHEVVNTWHSDAENYNYENGKGPAGNFTQLVWSSTREVGFGKACGPGKCVVVAHYRPPGNVLGRYLENVFRPKKSVKDVKQPIRNTFALNNDTPKTVITETLTESDGKQYSVRREISDLTDDKGKNKKLYLVGQGKKVEYFSCCFNNRTRRCINEVYTDACKEQKKAKSSISPDGHLVDNSKKLQESIHSVVQLHNQYRSQHGSNPLVLDQNLSNMAQQWADHLLQQSHLSNSGYVYRGMKVGENLGSRWSNGPMELNCKDLIEHWYQESGKYKFNSEPDSIQGIGNFTQIVWTSSERIGVGIAIQSYKSGEDLHKDSKMILVCLYHPPGNVISQFQNNVKKAIK

Schistosoma mansoni Venom Allergen-like protein 11 (SmVAL11) is a 47 kDa protein composed by two symmetrical domains separated by a flexible linker. The latter, in our experience, undergoes autocleavage in vitro, with an unknown mechanism.