Structural Insights into the Interaction of the Intrinsically Disordered Co-activator TIF2 with Retinoic Acid Receptor Heterodimer (RXR/RAR).

Senicourt L, le Maire A, Allemand F, Carvalho JE, Guee L, Germain P, Schubert M, Bernadó P, Bourguet W, Sibille N
J Mol Biol 433(9):166899 (2021 Feb 27)
PMID: 33647291
doi: 10.1016/j.jmb.2021.166899
Submitted to SASBDB: 2021 Jan 27
Published in SASBDB:

SASDK68 – Transcriptional intermediary factor 2 (TIF2) intrinsically disordered coactivator

Nuclear receptor coactivator 2 experimental SAS data
Sample: Nuclear receptor coactivator 2 monomer, 16 kDa Homo sapiens protein
Buffer: 150 mM NaCl, 50 mM BisTris pH 6.8, and 0.5 mM EDTA, pH: 6.8
Experiment: SAXS data collected at EMBL P12, PETRA III on 2017 Jun 14
RgGuinier 3.7 nm
Dmax 16.3 nm
VolumePorod 50 nm3