TRYBE®: an Fc-free antibody format with three monovalent targeting arms engineered for long in vivo half-life.

Davé E, Durrant O, Dhami N, Compson J, Broadbridge J, Archer S, Maroof A, Whale K, Menochet K, Bonnaillie P, Barry E, Wild G, Peerboom C, Bhatta P, Ellis M, Hinchliffe M, Humphreys DP, Heywood SP
MAbs 15(1):2160229 (2023 Jan-Dec)
PMID: 36788124
doi: 10.1080/19420862.2022.2160229 		Submitted to SASBDB: 2021 Sep 16
Published in SASBDB:

SASDM45 – TrYbe® trispecific antibody

Tri-specific antibody experimental SAS data
OTHER model
Sample: Tri-specific antibody monomer, 102 kDa Homo sapiens protein
Buffer: PBS, pH: 7.4
Experiment: SAXS data collected at B21, Diamond Light Source on 2021 Apr 26
RgGuinier 4.1 nm
Dmax 13.0 nm
VolumePorod 157 nm3