Molecular basis of crosstalk in nuclear receptors: heterodimerization between PXR and CAR and the implication in gene regulation

SASDNZ3 – Heterodimerization between the nuclear receptor subfamily proteins PXR and CAR Sample: Nuclear receptor subfamily 1 group I member 2 monomer, 39 kDa Homo sapiens protein Nuclear receptor subfamily 1 group I member 3 monomer, 32 kDa Homo sapiens protein Buffer: 25 mM Hepes, 150 mM NaCl, 5% glycerol, 5 mM DTT, pH: 7.9 Experiment: SAXS data collected at 16-ID (LiX), National Synchrotron Light Source II (NSLS-II) on 2021 Oct 8 RgGuinier 2.7 nm Dmax 10.1 nm VolumePorod 56 nm3