PP2A is activated by cytochrome c upon formation of a diffuse encounter complex with SET/TAF-Iβ

Casado-Combreras M, Rivero-Rodríguez F, Elena-Real C, Molodenskiy D, Díaz-Quintana A, Martinho M, Gerbaud G, González-Arzola K, Velázquez-Campoy A, Svergun D, Belle V, De la Rosa M, Díaz-Moreno I
Computational and Structural Biotechnology Journal (2022 Jul)

doi: 10.1016/j.csbj.2022.07.009 		Submitted to SASBDB: 2022 Mar 16
Published in SASBDB:

SASDN77 – Truncated histone shaperone protein SET/TAF-Ib DC

SET nuclear proto-oncogene experimental SAS data
AMBER model
Sample: SET nuclear proto-oncogene dimer, 53 kDa Homo sapiens protein
Buffer: Sodium phosphate buffer, pH: 6.3
Experiment: SAXS data collected at EMBL P12, PETRA III on 2018 Nov 11
RgGuinier 3.1 nm
Dmax 9.7 nm
VolumePorod 87 nm3

SASDN87 – Mixture 1:2 of truncated histone shaperone protein SET/TAF-Ib DC with cytochrome c

Cytochrome cSET nuclear proto-oncogene experimental SAS data
SASREF model
Sample: Cytochrome c dimer, 24 kDa Homo sapiens protein
SET nuclear proto-oncogene dimer, 53 kDa Homo sapiens protein
Buffer: Sodium phosphate buffer, pH: 6.3
Experiment: SAXS data collected at EMBL P12, PETRA III on 2018 Nov 11
RgGuinier 4.2 nm
Dmax 16.0 nm