Visualizing gaussian-chain like structural models of human α-synuclein in monomeric pre-fibrillar state: Solution SAXS data and modeling analysis.

Dey M, Gupta A, Badmalia MD, Ashish, Sharma D
Int J Biol Macromol 288:138614 (2024 Dec 12)

PMID: 39674478 doi: 10.1016/j.ijbiomac.2024.138614

Submitted to SASBDB: 2022 Oct 31 Published in SASBDB: 2022 Nov 14

SASDQJ7 – Alpha Synuclein at 283 K and concentration of 8 mg/ml Sample: Human alpha-synuclein monomer, 14 kDa Homo sapiens protein Buffer: 10 mM HEPES, 50 mM NaCl, pH: 7.4 Experiment: SAXS data collected at Anton Paar SAXSpace, CSIR - Institute of Microbial Technology (IMTech) on 2015 Mar 18 RgGuinier 4.7 nm Dmax 17.6 nm VolumePorod 81 nm3

SASDQK7 – Alpha Synuclein at 283 K and concentration of 3.8 mg/ml Sample: Human alpha-synuclein monomer, 14 kDa Homo sapiens protein Buffer: 10 mM HEPES, 50 mM NaCl, pH: 7.4 Experiment: SAXS data collected at Anton Paar SAXSpace, CSIR - Institute of Microbial Technology (IMTech) on 2015 Mar 18 RgGuinier 4.7 nm Dmax 18.0 nm VolumePorod 76 nm3