One substrate many enzymes virtual screening uncovers missing genes of carnitine biosynthesis in human and mouse.

Malatesta M, Fornasier E, Di Salvo ML, Tramonti A, Zangelmi E, Peracchi A, Secchi A, Polverini E, Giachin G, Battistutta R, Contestabile R, Percudani R
Nat Commun 15(1):3199 (2024 Apr 13)
PMID: 38615009
doi: 10.1038/s41467-024-47466-3
Submitted to SASBDB: 2023 Aug 19
Published in SASBDB:

SASDSU8 – Threonine aldolase 1 tetramer at neutral pH

L-threonine aldolase experimental SAS data
PHENIX model
Sample: L-threonine aldolase tetramer, 165 kDa Mus musculus protein
Buffer: 20 mM Tris, 150 mM NaCl, 1 mM EDTA, 1 mM DTT, pH: 7.8
Experiment: SAXS data collected at BM29, ESRF on 2023 Feb 14
RgGuinier 3.7 nm
Dmax 10.6 nm
VolumePorod 209 nm3