Molecular structure and enzymatic mechanism of the human collagen hydroxylysine galactosyltransferase GLT25D1/COLGALT1

De Marco M, Rai S, Scietti L, Mattoteia D, Liberi S, Moroni E, Pinnola A, Vetrano A, Iacobucci C, Santambrogio C, Colombo G, Forneris F
Nature Communications 16(1) (2025 Apr 16)

doi: 10.1038/s41467-025-59017-5 		Submitted to SASBDB: 2024 Jun 21
Published in SASBDB:

SASDVZ2 – Human Collagen Galactosyltransferase GLT25D1/COLGALT1

Procollagen galactosyltransferase 1 experimental SAS data
CORAL model
Sample: Procollagen galactosyltransferase 1 dimer, 137 kDa Homo sapiens protein
Buffer: 25 mM HEPES, 0.1 M NaCl, pH: 8
Experiment: SAXS data collected at BM29, ESRF on 2022 Jun 5
RgGuinier 4.3 nm
Dmax 14.0 nm
VolumePorod 184 nm3