Inhibition of Mycobacterium tuberculosis UvrB by small molecules: Potent NER disruption and structural insights into dimer conformation.

Jahan F, Anand S, Kumar S, Pandey G, Siddiqi MI, Krishnan MY, Ramachandran R
Int J Biol Macromol :147338 (2025 Sep 3)

PMID: 40912432
doi: 10.1016/j.ijbiomac.2025.147338

Submitted to SASBDB: 2024 Jan 11
Published in SASBDB: 2025 Sep 8

SASDTT8 – UvrB (UvrABC system protein B)

Sample:	UvrABC system protein B dimer, 156 kDa Mycobacterium tuberculosis (strain … protein
Buffer:	50 mM Tris pH-8, 200 mM NaCl, 2% glycerol, pH:
Experiment:	SAXS data collected at Anton Paar SAXSpace, CSIR-Central Drug Research Institute on 2023 Jun 6