Structural heterogeneity and dynamics in the apical stem loop of s2m from SARS-CoV-2 Delta by an integrative NMR spectroscopy and MD simulation approach.

Wirtz Martin MA, Makowski JA, Matzel T, Kensinger AH, Herr A, Richter C, Jonker HRA, Wacker A, Evanseck JD, Schwalbe H
Nucleic Acids Res 53(12) (2025 Jun 20)

PMID: 40586311 doi: 10.1093/nar/gkaf552

Submitted to SASBDB: 2024 Jun 4 Published in SASBDB: 2025 Jul 21

SASDXB3 – Apical stem loop of stem loop 2 motif in Delta variant of SARS-CoV-2 (s2m Delta_short) Sample: Apical stem loop of stem loop 2 motif (s2m) in Delta variant of SARS-CoV-2 monomer, 8 kDa SARS-Coronavirus-2 Delta RNA Buffer: 50 mM Bis-Tris, 25 mM NaCl, pH: 6.4 Experiment: SAXS data collected at EMBL P12, PETRA III on 2022 Nov 30 RgGuinier 1.4 nm

SASDUD9 – Apical stem loop of stem loop 2 motif (s2m) in Delta variant of SARS-CoV-2 Sample: Apical stem loop of stem loop 2 motif (s2m) in Delta variant of SARS-CoV-2 monomer, 8 kDa SARS-Coronavirus-2 Delta RNA Buffer: 50 mM Bis-Tris, 25 mM NaCl, pH: 6.4 Experiment: SAXS data collected at EMBL P12, PETRA III on 2022 Nov 30 RgGuinier 1.5 nm