Biophysical analysis of an oligomerization-attenuated variant of the Leishmania donovani dynamin-1-like protein.

Wuyts E, Sundaramoorthy R, Tulloch L, Monsieurs P, Eadsforth TC, Pintelon I, Timmermans JP, Dujardin JC, Domagalska MA, Caljon G, De Rycker M, Postis VLG, Wyllie S, Sterckx YG
Mol Biochem Parasitol 263:111691 (2025 Aug 14)
PMID: 40818547
doi: 10.1016/j.molbiopara.2025.111691 		Submitted to SASBDB: 2025 Feb 5
Published in SASBDB:

SASDWB7 – Dynamin central region family protein from Leishmania donovani DLP1 G354D / R357S

Dynamin central region family protein experimental SAS data
BILBOMD model
Sample: Dynamin central region family protein dimer, 165 kDa Leishmania donovani protein
Buffer: 20 mM HEPES, 200 mM NaCl, 3% glycerol, pH: 7.4
Experiment: SAXS data collected at SWING, SOLEIL on 2024 Apr 4
RgGuinier 6.6 nm
Dmax 25.0 nm
VolumePorod 340 nm3