pH Sensitivity of the SERF1a Conformational Ensemble

Huang S, Shih O, Jeng U, Chang C, Lin J, Malliavin T
ACS Omega (2026 Jan 05)

doi: 10.1021/acsomega.5c07620 		Submitted to SASBDB: 2025 Mar 6
Published in SASBDB:

SASDWZ9 – Small EDRK-rich factor 1 protein (SERF1a) at pH 6.8

Isoform Short of Small EDRK-rich factor 1 experimental SAS data
OTHER model
Sample: Isoform Short of Small EDRK-rich factor 1 monomer, 7 kDa Homo sapiens protein
Buffer: 20 mM sodium phosphate, 20 mM NaCl, pH: 6.8
Experiment: SAXS data collected at 13A, Taiwan Photon Source, NSRRC on 2023 Mar 9
RgGuinier 2.5 nm
Dmax 8.8 nm
VolumePorod 11 nm3

SASDWY9 – Small EDRK-rich factor 1 protein (SERF1a) at pH 6

Isoform Short of Small EDRK-rich factor 1 experimental SAS data
OTHER model
Sample: Isoform Short of Small EDRK-rich factor 1 monomer, 7 kDa Homo sapiens protein
Buffer: 20 mM sodium phosphate, 20 mM NaCl, pH: 6
Experiment: SAXS data collected at 13A, Taiwan Photon Source, NSRRC on 2023 Mar 9
RgGuinier 2.4 nm
Dmax 10.3 nm
VolumePorod 10 nm3