Multi-domain O-GlcNAcase structures reveal allosteric regulatory mechanisms.

Hansen SB, Bartual SG, Yuan H, Raimi OG, Gorelik A, Ferenbach AT, Lytje K, Pedersen JS, Drace T, Boesen T, van Aalten DMF
Nat Commun 16(1):8828 (2025 Oct 3)
PMID: 41044083
doi: 10.1038/s41467-025-63893-2 		Submitted to SASBDB: 2025 Apr 2
Published in SASBDB:

SASDXF3 – RTX cytotoxin pro-MbxA without acylation (pro-MbxA)

RTX cytotoxin pro-MbxA without acylation experimental SAS data
ALPHAFOLD model
Sample: RTX cytotoxin pro-MbxA without acylation monomer, 100 kDa Moraxella bovis protein
Buffer: 50 mM Tris, 100 mM NaCl, 10mM CaCl2, pH: 7.8
Experiment: SAXS data collected at EMBL P12, PETRA III on 2022 May 9
RgGuinier 3.8 nm
Dmax 13.4 nm
VolumePorod 154 nm3