The major diagnostic VSG LiTat 1.3 of the human parasite Trypanosoma brucei gambiense is a trimer in solution

Danel N, Geens R, Mares-Mejía I, Versées W, Van Den Abbeele J, Sterckx Y, Soldati-Favre D
PLOS Pathogens 22(8):e1014530 (2026 Aug 10)

doi: 10.1371/journal.ppat.1014530 		Submitted to SASBDB: 2025 Sep 16
Published in SASBDB:

SASDXA9 – Trypanosoma brucei gambiense, Variant Surface Glycoprotein (VSG) LiTat 1.3

Variant surface glycoprotein LiTat 1.3 experimental SAS data
BILBOMD model
Sample: Variant surface glycoprotein LiTat 1.3 trimer, 145 kDa Trypanosoma brucei gambiense protein
Buffer: 20 mM HEPES, 150 mM NaCl, 3% glycerol, pH: 7.4
Experiment: SAXS data collected at SWING, SOLEIL on 2024 Apr 4
RgGuinier 4.8 nm
Dmax 16.5 nm
VolumePorod 252 nm3