Structural and biophysical analysis of the four CHRD domains of human chordin reveals a novel binding site for glycosaminoglycans.

Snee M, Birchenough HL, Becker MH, Popplewell JF, Ashe HL, Baldock C
J Biol Chem :113248 (2026 Jun 12)
PMID: 42285510
doi: 10.1016/j.jbc.2026.113248 		Submitted to SASBDB: 2026 Jan 27
Published in SASBDB:

SASDY96 – Chordin fragment aa.168-650

Chordin fragment aa.168-650 experimental SAS data
MULTIFOXS model
Sample: Chordin fragment aa.168-650 monomer, 54 kDa Homo sapiens protein
Buffer: 25 mM HEPES, 150 mM NaCl, pH: 7.5
Experiment: SAXS data collected at B21, Diamond Light Source on 2024 Jul 26
RgGuinier 3.0 nm
Dmax 10.6 nm
VolumePorod 106 nm3