Single-engineered-residue solvation perturbations regulate global protein architecture and function.

Liu Y, Zhai J, Cao S, Guo H, Zhang H, Song B, Guo J, Men D, He X, Li D
Nat Commun (2026 Mar 10)

PMID: 41807374
doi: 10.1038/s41467-026-70155-2

Submitted to SASBDB: 2026 Feb 13
Published in SASBDB: 2026 Mar 16

SASDY97 – Alkaline phosphatase (ALP) under vis

Sample:	Wild Alkaline Phosphatase under vis dimer, 97 kDa Escherichia coli protein
Buffer:	25 mM Tris, 100 mM NaCl, 2 mM TCEP, 3% (w/v) glycerol, pH: 7.5
Experiment:	SAXS data collected at BL19U2, Shanghai Synchrotron Radiation Facility (SSRF) on 2024 Dec 23