High-resolution structure of the vaccinia virus phospholipase D-fold endonuclease K4.

Gröger H, Trouba C, Barbaste J, Lacroix G, Schoehn G, Burmeister WP, Tarbouriech N
J Mol Biol :169961 (2026 Jul 29)
PMID: 42526583
doi: 10.1016/j.jmb.2026.169961 		Submitted to SASBDB: 2026 May 14
Published in SASBDB:

SASDZ78 – Octameric Assembly of the Phospholipase D–Like (PLD-Fold) Nuclease K4 Domain in the Vaccinia Virion Nicking-Joining Enzyme

Virion nicking-joining enzyme (octamer) experimental SAS data
PHENIX model
Sample: Virion nicking-joining enzyme (octamer) octamer, 393 kDa Vaccinia virus (strain … protein
Buffer: 20 mM Tris pH 7.5, 150 mM NaCl, 0.5mM TCEP, pH: 7.5
Experiment: SAXS data collected at SWING, SOLEIL on 2024 Oct 14
RgGuinier 5.0 nm
Dmax 18.0 nm
VolumePorod 491 nm3