The solution structure and dynamics of the DH-PH module of PDZRhoGEF in isolation and in complex with nucleotide-free RhoA.
Cierpicki T,
Bielnicki J,
Zheng M,
Gruszczyk J,
Kasterka M,
Petoukhov M,
Zhang A,
Fernandez EJ,
Svergun DI,
Derewenda U,
Bushweller JH,
Derewenda ZS
Protein Sci
18(10):2067-79
(2009 Oct)
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| Sample: |
DH-PH module of PDZRhoGEF monomer, 41 kDa Homo sapiens protein
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| Buffer: |
50 mM Tris-HCL 150 mM NaCl 1.0 mM DTT, pH: 7.5 |
| Experiment: |
SAXS
data collected at EMBL X33, DORIS III, DESY on 2008 Oct 30
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| RgGuinier |
2.9 |
nm |
| Dmax |
9.0 |
nm |
| VolumePorod |
60 |
nm3 |
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