Structural underpinnings of Ric8A function as a G-protein α-subunit chaperone and guanine-nucleotide exchange factor.

Srivastava D, Gakhar L, Artemyev NO
Nat Commun 10(1):3084 (2019 Jul 12)

PMID: 31300652 doi: 10.1038/s41467-019-11088-x

Submitted to SASBDB: 2019 Mar 27 Published in SASBDB: 2019 Jun 17

SASDF65 – Resistance to inhibitors of cholinesterase 8 homolog A (Ric8a) amino acids 1-492 Sample: Resistance to inhibitors of cholinesterase 8 homolog A monomer, 56 kDa Bos taurus protein Buffer: 20 mM Tris, 150 mM KCl, 5 % glycerol, 1 mM TCEP, pH: 8 Experiment: SAXS data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2018 Oct 27 RgGuinier 3.4 nm Dmax 12.7 nm VolumePorod 88 nm3

SASDF75 – Resistance to inhibitors of cholinesterase 8 homolog A (Ric8a) amino acids 1-452 Sample: Resistance to inhibitors of cholinesterase 8 homolog A monomer, 51 kDa Bos taurus protein Buffer: 20 mM Tris, 150 mM KCl, 5 % glycerol, 1 mM TCEP, pH: 8 Experiment: SAXS data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2018 Oct 27 RgGuinier 3.0 nm Dmax 11.2 nm VolumePorod 70 nm3