Structure of the G protein chaperone and guanine nucleotide exchange factor Ric-8A bound to Gαi1

McClelland L, Zhang K, Mou T, Johnston J, Yates-Hansen C, Li S, Thomas C, Doukov T, Triest S, Wohlkonig A, Tall G, Steyaert J, Chiu W, Sprang S
Nature Communications 11(1) (2020 Feb 26)

doi: 10.1038/s41467-020-14943-4
Submitted to SASBDB: 2019 Sep 13
Published in SASBDB:

SASDG95 – Phosphorylated resistance to inhibitors of cholinesterase 8 homolog A (Ric-8A, 1-491) and G protein complex

Resistance to inhibitors of cholinesterase 8 homolog AGuanine nucleotide-binding protein G(i) subunit alpha-1 experimental SAS data
DAMMIF model
Sample: Resistance to inhibitors of cholinesterase 8 homolog A monomer, 56 kDa Rattus norvegicus protein
Guanine nucleotide-binding protein G(i) subunit alpha-1 monomer, 38 kDa Rattus norvegicus protein
Buffer: 25 mM HEPES, 150 mM NaCl, pH: 8
Experiment: SAXS data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2019 Jul 30
RgGuinier 3.5 nm
Dmax 11.5 nm
VolumePorod 120 nm3