Flexible Structure of Peptide-Bound Filamin A Mechanosensor Domain Pair 20-21.

Seppälä J, Tossavainen H, Rodic N, Permi P, Pentikäinen U, Ylänne J
PLoS One 10(8):e0136969 (2015)

PMID: 26322797 doi: 10.1371/journal.pone.0136969

Submitted to SASBDB: 2015 May 28 Published in SASBDB: 2016 Jul 18

SASDAE8 – Human Filamin A Ig-like domains 20-21 truncation (2151-2329) in complex with migfilin peptide Sample: Human Filamin A Ig-like domains 20-21/migfilin peptide complex monomer, 21 kDa Homo sapiens protein Buffer: 20 mM Tris 50 mM NaCl 10mM DTT, pH: 8 Experiment: SAXS data collected at BM29, ESRF on 2014 Feb 1 RgGuinier 2.4 nm Dmax 8.2 nm VolumePorod 31 nm3

SASDAF8 – Human Filamin A Ig-like domains 20-21 truncation (2151-2329) Sample: Human Filamin A Ig-like domains 20-21 monomer, 19 kDa Homo sapiens protein Buffer: 20 mM Tris 50 mM NaCl 10mM DTT, pH: 8 Experiment: SAXS data collected at BM29, ESRF on 2014 Feb 1 RgGuinier 2.4 nm Dmax 8.5 nm VolumePorod 29 nm3

SASDAG8 – Human Filamin A Ig-like domains 20-21* truncation (2141-2329) in complex with migfilin peptide Sample: Human Filamin A Ig-like domains 20-21*/migfilin peptide complex monomer, 23 kDa Homo sapiens protein Buffer: 20 mM Tris 50 mM NaCl 10mM DTT, pH: 8 Experiment: SAXS data collected at BM29, ESRF on 2014 Feb 1 RgGuinier 2.4 nm Dmax 8.2 nm VolumePorod 33 nm3

SASDAH8 – Human Filamin A Ig-like domains 20-21* truncation (2141-2329) Sample: Human Filamin A Ig-like domains 20-21* monomer, 20 kDa Homo sapiens protein Buffer: 20 mM Tris 50 mM NaCl 10mM DTT, pH: 8 Experiment: SAXS data collected at BM29, ESRF on 2014 Feb 1 RgGuinier 1.9 nm Dmax 6.8 nm VolumePorod 32 nm3