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3 hits found for Methyltransferase domain protein

SASDDJ6 – ...Methyltransferase from Mycobacterium hassiacum

Methyltransferase domain protein experimental SAS data
MODELLER model
Sample: Methyltransferase domain protein dimer, 51 kDa Mycolicibacterium hassiacum protein
Buffer: 20 mM bis-tris propane, 50 mM NaCl, 2 mM DTT, 5% (v/v) glycerol, pH: 7.5
Experiment: SAXS data collected at BM29, ESRF on 2017 Jun 21
...methyltransferase specific for 3-O-methylated mannosides. Proc Natl Acad Sci U S A 116(3):835-844 (2019)
Ripoll-Rozada J, Costa M, Manso JA, Maranha A, Miranda V, Sequeira A, Ventura MR, Macedo-Ribeiro S, Pereira PJB, Empadinhas N
RgGuinier 2.6 nm
Dmax 8.5 nm
VolumePorod 86 nm3

SASDVZ8 – ...domain from human DNA (cytosine-5)-methyltransferase 3B (DNMT3B)

DNA (cytosine-5)-methyltransferase 3B Pro-Trp-Trp-Pro (PWWP) domain experimental SAS data
GASBOR model
Sample: ...methyltransferase 3B Pro-Trp-Trp-Pro (PWWP) domain monomer, 17 kDa Homo sapiens protein
Buffer: 20 mM Tris, 300 mM NaCl, 1 mM TCEP, 5% glycerol, pH: 8
Experiment: SAXS data collected at 13A, Taiwan Photon Source, NSRRC on 2024 Apr 20
Histone modification-driven structural remodeling unleashes DNMT3B in DNA methylation. Sci Adv 11(13):eadu8116 (2025)
Cho CC, Huang HH, Jiang BC, Yang WZ, Chen YN, Yuan HS
RgGuinier 1.8 nm
Dmax 6.4 nm
VolumePorod 20464 nm3

SASDVK9 – ...domain from human DNA (cytosine-5)-methyltransferase 3B (DNMT3B) in complex with histone H3

Histone H3.3DNA (cytosine-5)-methyltransferase 3B Pro-Trp-Trp-Pro (PWWP) domain experimental SAS data
GASBOR model
Sample: Histone H3.3 monomer, 4 kDa Homo sa protein
...methyltransferase 3B Pro-Trp-Trp-Pro (PWWP) domain monomer, 17 kDa Homo sapiens protein
Buffer: 20 mM Tris, 300 mM NaCl, 1 mM TCEP, 5% glycerol, pH: 8
Experiment: SAXS data collected at 13A, Taiwan Photon Source, NSRRC on 2024 Sep 17
Histone modification-driven structural remodeling unleashes DNMT3B in DNA methylation. Sci Adv 11(13):eadu8116 (2025)
Cho CC, Huang HH, Jiang BC, Yang WZ, Chen YN, Yuan HS
RgGuinier 1.8 nm
Dmax 7.4 nm
VolumePorod 19 nm3