2 hits found for humanized immunoglobulin G4 monoclonal antibody (lebrikizumab)

SASDW44 – Immunoglobulin G4 (pH 2, 0.2 M NaCl), SEC-SAXS data Sample: humanized immunoglobulin G4 monoclonal antibody (lebrikizumab) monomer, 148 kDa Mouse/human protein Buffer: 100 mM glycine-HCl, 200 mM NaCl, pH: 2 Experiment: SAXS data collected at BL-10C, Photon Factory (PF), High Energy Accelerator Research Organization (KEK) on 2024 Nov 19 ...G4 and IgG1 undergo common acid‐induced compaction into an alternatively folded state FEBS Letters (2025) Imamura H, Honda S RgGuinier 4.1 nm Dmax 14.0 nm VolumePorod 238 nm3

SASDW64 – Immunoglobulin G4 (pH 7) Sample: humanized immunoglobulin G4 monoclonal antibody (lebrikizumab) monomer, 148 kDa Mouse/human protein Buffer: 10 mM sodium phosphate, pH: 7 Experiment: SAXS data collected at BL-10C, Photon Factory (PF), High Energy Accelerator Research Organization (KEK) on 2024 Nov 19 ...G4 and IgG1 undergo common acid‐induced compaction into an alternatively folded state FEBS Letters (2025) Imamura H, Honda S RgGuinier 4.8 nm Dmax 15.6 nm VolumePorod 211 nm3