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19 hits found for Alpha-aminoadipic semialdehyde dehydrogenase

SASDCH2 – ...dehydrogenase 7A1

Aldehyde dehydrogenase 7A1 (Alpha-aminoadipic semialdehyde dehydrogenase) experimental SAS data
NONE model
Sample: ...dehydrogenase 7A1 (Alpha-aminoadipic semialdehyde dehydrogenase) tetramer, 222 kDa Homo sapiens protein
Buffer: 50 mM Tris, 5% glycerol, 0.5 mM tris(3-hydroxypropyl)phosphine, 50 mM NaCl, pH: 7.8
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2014 Mar 9
...Dehydrogenase 7A1. Biochemistry 54(35):5513-22 (2015)
Luo M, Tanner JJ
RgGuinier 3.8 nm
Dmax 11.5 nm
VolumePorod 270 nm3

SASDGH4 – ...alpha-aminoadipic semialdehyde dehydrogenase (ALDH)7A1 at 1.2 mg/mL

Alpha-aminoadipic semialdehyde dehydrogenase experimental SAS data
PDB model
Sample: Alpha-aminoadipic semialdehyde dehydrogenase tetramer, 222 kDa Homo sapiens protein
Buffer: 50 mM HEPES, 100 mM NaCl, 1 mM DTT, 10 mM NAD, 2% (v/v) glycerol, pH: 8
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2019 May 1
Structural Analysis of Pathogenic Mutations Targeting Glu427 of ALDH7A1, the Hot Spot Residue of Pyridoxine-Dependent Epilepsy. J Inherit Metab Dis (2019)
Laciak AR, Korasick DA, Gates KS, Tanner JJ
RgGuinier 3.8 nm
Dmax 11.5 nm
VolumePorod 350 nm3

SASDGJ4 – ...alpha-aminoadipic semialdehyde dehydrogenase (ALDH)7A1 at 2.3 mg/mL

Alpha-aminoadipic semialdehyde dehydrogenase experimental SAS data
PDB model
Sample: Alpha-aminoadipic semialdehyde dehydrogenase tetramer, 222 kDa Homo sapiens protein
Buffer: 50 mM HEPES, 100 mM NaCl, 1 mM DTT, 10 mM NAD, 2% (v/v) glycerol, pH: 8
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2019 May 1
Structural Analysis of Pathogenic Mutations Targeting Glu427 of ALDH7A1, the Hot Spot Residue of Pyridoxine-Dependent Epilepsy. J Inherit Metab Dis (2019)
Laciak AR, Korasick DA, Gates KS, Tanner JJ
RgGuinier 3.8 nm
Dmax 10.7 nm
VolumePorod 326 nm3

SASDGK4 – ...alpha-aminoadipic semialdehyde dehydrogenase (ALDH)7A1 at 4.7 mg/mL

Alpha-aminoadipic semialdehyde dehydrogenase experimental SAS data
PDB model
Sample: Alpha-aminoadipic semialdehyde dehydrogenase tetramer, 222 kDa Homo sapiens protein
Buffer: 50 mM HEPES, 100 mM NaCl, 1 mM DTT, 10 mM NAD, 2% (v/v) glycerol, pH: 8
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2019 May 1
Structural Analysis of Pathogenic Mutations Targeting Glu427 of ALDH7A1, the Hot Spot Residue of Pyridoxine-Dependent Epilepsy. J Inherit Metab Dis (2019)
Laciak AR, Korasick DA, Gates KS, Tanner JJ
RgGuinier 3.8 nm
Dmax 10.7 nm
VolumePorod 315 nm3

SASDGL4 – ...alpha-aminoadipic semialdehyde dehydrogenase (ALDH)7A1 E399Q at 1.1 mg/mL

Alpha-aminoadipic semialdehyde dehydrogenase E399Q experimental SAS data
PDB model
Sample: Alpha-aminoadipic semialdehyde dehydrogenase E399Q , 56 kDa Homo sapiens protein
Buffer: 50 mM HEPES, 100 mM NaCl, 1 mM DTT, 10 mM NAD, 2% (v/v) glycerol, pH: 8
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2019 May 1
Structural Analysis of Pathogenic Mutations Targeting Glu427 of ALDH7A1, the Hot Spot Residue of Pyridoxine-Dependent Epilepsy. J Inherit Metab Dis (2019)
Laciak AR, Korasick DA, Gates KS, Tanner JJ
RgGuinier 3.7 nm
Dmax 10.3 nm
VolumePorod 237 nm3

SASDGM4 – ...alpha-aminoadipic semialdehyde dehydrogenase (ALDH)7A1 E399Q at 2.1 mg/mL

Alpha-aminoadipic semialdehyde dehydrogenase E399Q experimental SAS data
PDB model
Sample: Alpha-aminoadipic semialdehyde dehydrogenase E399Q , 56 kDa Homo sapiens protein
Buffer: 50 mM HEPES, 100 mM NaCl, 1 mM DTT, 10 mM NAD, 2% (v/v) glycerol, pH: 8
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2019 May 1
Structural Analysis of Pathogenic Mutations Targeting Glu427 of ALDH7A1, the Hot Spot Residue of Pyridoxine-Dependent Epilepsy. J Inherit Metab Dis (2019)
Laciak AR, Korasick DA, Gates KS, Tanner JJ
RgGuinier 3.8 nm
Dmax 10.8 nm
VolumePorod 238 nm3

SASDGN4 – ...alpha-aminoadipic semialdehyde dehydrogenase (ALDH)7A1 E399Q at 4.3 mg/mL

Alpha-aminoadipic semialdehyde dehydrogenase E399Q experimental SAS data
PDB model
Sample: Alpha-aminoadipic semialdehyde dehydrogenase E399Q , 56 kDa Homo sapiens protein
Buffer: 50 mM HEPES, 100 mM NaCl, 1 mM DTT, 10 mM NAD, 2% (v/v) glycerol, pH: 8
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2019 May 1
Structural Analysis of Pathogenic Mutations Targeting Glu427 of ALDH7A1, the Hot Spot Residue of Pyridoxine-Dependent Epilepsy. J Inherit Metab Dis (2019)
Laciak AR, Korasick DA, Gates KS, Tanner JJ
RgGuinier 3.8 nm
Dmax 10.6 nm
VolumePorod 255 nm3

SASDGP4 – ...alpha-aminoadipic semialdehyde dehydrogenase (ALDH)7A1 E399D at 1.4 mg/mL

Alpha-aminoadipic semialdehyde dehydrogenase experimental SAS data
PDB model
Sample: Alpha-aminoadipic semialdehyde dehydrogenase , 56 kDa Homo sapiens protein
Buffer: 50 mM HEPES, 100 mM NaCl, 1 mM DTT, 10 mM NAD, 2% (v/v) glycerol, pH: 8
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2019 May 1
Structural Analysis of Pathogenic Mutations Targeting Glu427 of ALDH7A1, the Hot Spot Residue of Pyridoxine-Dependent Epilepsy. J Inherit Metab Dis (2019)
Laciak AR, Korasick DA, Gates KS, Tanner JJ
RgGuinier 3.7 nm
Dmax 11.3 nm
VolumePorod 256 nm3

SASDGQ4 – ...alpha-aminoadipic semialdehyde dehydrogenase (ALDH)7A1 E399D at 2.9 mg/mL

Alpha-aminoadipic semialdehyde dehydrogenase experimental SAS data
PDB model
Sample: Alpha-aminoadipic semialdehyde dehydrogenase , 56 kDa Homo sapiens protein
Buffer: 50 mM HEPES, 100 mM NaCl, 1 mM DTT, 10 mM NAD, 2% (v/v) glycerol, pH: 8
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2019 May 1
Structural Analysis of Pathogenic Mutations Targeting Glu427 of ALDH7A1, the Hot Spot Residue of Pyridoxine-Dependent Epilepsy. J Inherit Metab Dis (2019)
Laciak AR, Korasick DA, Gates KS, Tanner JJ
RgGuinier 3.8 nm
Dmax 11.4 nm
VolumePorod 260 nm3

SASDGR4 – ...alpha-aminoadipic semialdehyde dehydrogenase (ALDH)7A1 E399D at 5.7 mg/mL

Alpha-aminoadipic semialdehyde dehydrogenase E399D experimental SAS data
PDB model
Sample: Alpha-aminoadipic semialdehyde dehydrogenase E399D , 56 kDa Homo sapiens protein
Buffer: 50 mM HEPES, 100 mM NaCl, 1 mM DTT, 10 mM NAD, 2% (v/v) glycerol, pH: 8
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2019 May 1
Structural Analysis of Pathogenic Mutations Targeting Glu427 of ALDH7A1, the Hot Spot Residue of Pyridoxine-Dependent Epilepsy. J Inherit Metab Dis (2019)
Laciak AR, Korasick DA, Gates KS, Tanner JJ
RgGuinier 3.9 nm
Dmax 10.6 nm
VolumePorod 272 nm3

SASDGS4 – ...alpha-aminoadipic semialdehyde dehydrogenase (ALDH)7A1 E399G at 1.6 mg/mL

Alpha-aminoadipic semialdehyde dehydrogenase E399G experimental SAS data
PDB model
Sample: Alpha-aminoadipic semialdehyde dehydrogenase E399G , 55 kDa Homo sapiens protein
Buffer: 50 mM HEPES, 100 mM NaCl, 1 mM DTT, 10 mM NAD, 2% (v/v) glycerol, pH: 8
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2019 May 1
Structural Analysis of Pathogenic Mutations Targeting Glu427 of ALDH7A1, the Hot Spot Residue of Pyridoxine-Dependent Epilepsy. J Inherit Metab Dis (2019)
Laciak AR, Korasick DA, Gates KS, Tanner JJ
RgGuinier 3.8 nm
Dmax 11.3 nm
VolumePorod 290 nm3

SASDGT4 – ...alpha-aminoadipic semialdehyde dehydrogenase (ALDH)7A1 E399G at 3.2 mg/mL

Alpha-aminoadipic semialdehyde dehydrogenase E399G experimental SAS data
PDB model
Sample: Alpha-aminoadipic semialdehyde dehydrogenase E399G , 55 kDa Homo sapiens protein
Buffer: 50 mM HEPES, 100 mM NaCl, 1 mM DTT, 10 mM NAD, 2% (v/v) glycerol, pH: 8
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2019 May 1
Structural Analysis of Pathogenic Mutations Targeting Glu427 of ALDH7A1, the Hot Spot Residue of Pyridoxine-Dependent Epilepsy. J Inherit Metab Dis (2019)
Laciak AR, Korasick DA, Gates KS, Tanner JJ
RgGuinier 3.7 nm
Dmax 10.6 nm
VolumePorod 250 nm3

SASDGU4 – ...alpha-aminoadipic semialdehyde dehydrogenase (ALDH)7A1 E399G at 6.5 mg/mL

Alpha-aminoadipic semialdehyde dehydrogenase E399G experimental SAS data
PDB model
Sample: Alpha-aminoadipic semialdehyde dehydrogenase E399G , 55 kDa Homo sapiens protein
Buffer: 50 mM HEPES, 100 mM NaCl, 1 mM DTT, 10 mM NAD, 2% (v/v) glycerol, pH: 8
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2019 May 1
Structural Analysis of Pathogenic Mutations Targeting Glu427 of ALDH7A1, the Hot Spot Residue of Pyridoxine-Dependent Epilepsy. J Inherit Metab Dis (2019)
Laciak AR, Korasick DA, Gates KS, Tanner JJ
RgGuinier 3.8 nm
Dmax 10.0 nm
VolumePorod 270 nm3

SASDD29 – ...alpha-aminoadipic semialdehyde dehydrogenase (ALDH7A1) collected by SEC-SAXS

Alpha-aminoadipic semialdehyde dehydrogenase experimental SAS data
PDB model
Sample: Alpha-aminoadipic semialdehyde dehydrogenase tetramer, 222 kDa Homo sapiens protein
Buffer: 50 mM Tris, 50 mM NaCl, 0.5 mM DTT, 5% (v/v) glycerol, pH: 7.8
Experiment: SAXS data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2018 Feb 22
...Dehydrogenase 7A1. FEBS Lett (2018)
Korasick DA, White TA, Chakravarthy S, Tanner JJ
RgGuinier 3.5 nm
VolumePorod 212 nm3

SASDD39 – ...alpha-aminoadipic semialdehyde dehydrogenase (ALDH7A1) collected by SEC-SAXS

Alpha-aminoadipic semialdehyde dehydrogenase experimental SAS data
PDB model
Sample: Alpha-aminoadipic semialdehyde dehydrogenase tetramer, 222 kDa Homo sapiens protein
Buffer: 50 mM Tris, 50 mM NaCl, 0.5 mM DTT, 5% (v/v) glycerol, pH: 7.8
Experiment: SAXS data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2018 Feb 22
...Dehydrogenase 7A1. FEBS Lett (2018)
Korasick DA, White TA, Chakravarthy S, Tanner JJ
RgGuinier 3.7 nm
VolumePorod 229 nm3

SASDD49 – ...alpha-aminoadipic semialdehyde dehydrogenase (ALDH7A1) collected by SEC-SAXS

Alpha-aminoadipic semialdehyde dehydrogenase experimental SAS data
PDB model
Sample: Alpha-aminoadipic semialdehyde dehydrogenase tetramer, 222 kDa Homo sapiens protein
Buffer: 50 mM Tris, 50 mM NaCl, 0.5 mM DTT, 5% (v/v) glycerol, pH: 7.8
Experiment: SAXS data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2018 Feb 22
...Dehydrogenase 7A1. FEBS Lett (2018)
Korasick DA, White TA, Chakravarthy S, Tanner JJ
RgGuinier 3.7 nm
VolumePorod 238 nm3

SASDD59 – ...alpha-aminoadipic semialdehyde dehydrogenase (ALDH7A1) with nicotinamide adenine dinucleotide (NAD) collected by SEC-SAXS

Alpha-aminoadipic semialdehyde dehydrogenase experimental SAS data
PDB model
Sample: Alpha-aminoadipic semialdehyde dehydrogenase tetramer, 222 kDa Homo sapiens protein
Buffer: 50 mM Tris, 50 mM NaCl, 0.5 mM DTT, 5% (v/v) glycerol, 1 mM NAD, pH: 7.8
Experiment: SAXS data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2018 Feb 22
...Dehydrogenase 7A1. FEBS Lett (2018)
Korasick DA, White TA, Chakravarthy S, Tanner JJ
RgGuinier 3.7 nm
VolumePorod 277 nm3

SASDD69 – ...alpha-aminoadipic semialdehyde dehydrogenase (ALDH7A1) with nicotinamide adenine dinucleotide (NAD) collected by SEC-SAXS

Alpha-aminoadipic semialdehyde dehydrogenase experimental SAS data
PDB model
Sample: Alpha-aminoadipic semialdehyde dehydrogenase tetramer, 222 kDa Homo sapiens protein
Buffer: 50 mM Tris, 50 mM NaCl, 0.5 mM DTT, 5% (v/v) glycerol, 1 mM NAD, pH: 7.8
Experiment: SAXS data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2018 Feb 22
...Dehydrogenase 7A1. FEBS Lett (2018)
Korasick DA, White TA, Chakravarthy S, Tanner JJ
RgGuinier 3.8 nm
VolumePorod 275 nm3

SASDD79 – ...alpha-aminoadipic semialdehyde dehydrogenase ALDH7A1 with nicotinamide adenine dinucleotide (NAD) collected by SEC-SAXS

Alpha-aminoadipic semialdehyde dehydrogenase experimental SAS data
PDB model
Sample: Alpha-aminoadipic semialdehyde dehydrogenase tetramer, 222 kDa Homo sapiens protein
Buffer: 50 mM Tris, 50 mM NaCl, 0.5 mM DTT, 5% (v/v) glycerol, 1 mM NAD, pH: 7.8
Experiment: SAXS data collected at BioCAT 18ID, Advanced Photon Source (APS), Argonne National Laboratory on 2018 Feb 22
...Dehydrogenase 7A1. FEBS Lett (2018)
Korasick DA, White TA, Chakravarthy S, Tanner JJ
RgGuinier 3.8 nm
VolumePorod 277 nm3