SASBDB entries for UniProt ID: P49419

SASDGL4 – Human alpha-aminoadipic semialdehyde dehydrogenase (ALDH)7A1 E399Q at 1.1 mg/mL

UniProt ID: P49419 (None-None) Alpha-aminoadipic semialdehyde dehydrogenase E399Q
Alpha-aminoadipic semialdehyde dehydrogenase E399Q experimental SAS data
PDB (PROTEIN DATA BANK) model
Sample: Alpha-aminoadipic semialdehyde dehydrogenase E399Q, 56 kDa Homo sapiens protein
Buffer: 50 mM HEPES, 100 mM NaCl, 1 mM DTT, 10 mM NAD, 2% (v/v) glycerol, pH: 8
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2019 May 1
Structural Analysis of Pathogenic Mutations Targeting Glu427 of ALDH7A1, the Hot Spot Residue of Pyridoxine-Dependent Epilepsy. J Inherit Metab Dis (2019)
Laciak AR, Korasick DA, Gates KS, Tanner JJ
RgGuinier 3.7 nm
Dmax 10.3 nm
VolumePorod 237 nm3

SASDGM4 – Human alpha-aminoadipic semialdehyde dehydrogenase (ALDH)7A1 E399Q at 2.1 mg/mL

UniProt ID: P49419 (None-None) Alpha-aminoadipic semialdehyde dehydrogenase E399Q
Alpha-aminoadipic semialdehyde dehydrogenase E399Q experimental SAS data
PDB (PROTEIN DATA BANK) model
Sample: Alpha-aminoadipic semialdehyde dehydrogenase E399Q, 56 kDa Homo sapiens protein
Buffer: 50 mM HEPES, 100 mM NaCl, 1 mM DTT, 10 mM NAD, 2% (v/v) glycerol, pH: 8
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2019 May 1
Structural Analysis of Pathogenic Mutations Targeting Glu427 of ALDH7A1, the Hot Spot Residue of Pyridoxine-Dependent Epilepsy. J Inherit Metab Dis (2019)
Laciak AR, Korasick DA, Gates KS, Tanner JJ
RgGuinier 3.8 nm
Dmax 10.8 nm
VolumePorod 238 nm3

SASDGN4 – Human alpha-aminoadipic semialdehyde dehydrogenase (ALDH)7A1 E399Q at 4.3 mg/mL

UniProt ID: P49419 (None-None) Alpha-aminoadipic semialdehyde dehydrogenase E399Q
Alpha-aminoadipic semialdehyde dehydrogenase E399Q experimental SAS data
PDB (PROTEIN DATA BANK) model
Sample: Alpha-aminoadipic semialdehyde dehydrogenase E399Q, 56 kDa Homo sapiens protein
Buffer: 50 mM HEPES, 100 mM NaCl, 1 mM DTT, 10 mM NAD, 2% (v/v) glycerol, pH: 8
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2019 May 1
Structural Analysis of Pathogenic Mutations Targeting Glu427 of ALDH7A1, the Hot Spot Residue of Pyridoxine-Dependent Epilepsy. J Inherit Metab Dis (2019)
Laciak AR, Korasick DA, Gates KS, Tanner JJ
RgGuinier 3.8 nm
Dmax 10.6 nm
VolumePorod 255 nm3

SASDGP4 – Human alpha-aminoadipic semialdehyde dehydrogenase (ALDH)7A1 E399D at 1.4 mg/mL

UniProt ID: P49419 (None-None) Alpha-aminoadipic semialdehyde dehydrogenase
Alpha-aminoadipic semialdehyde dehydrogenase experimental SAS data
PDB (PROTEIN DATA BANK) model
Sample: Alpha-aminoadipic semialdehyde dehydrogenase, 56 kDa Homo sapiens protein
Buffer: 50 mM HEPES, 100 mM NaCl, 1 mM DTT, 10 mM NAD, 2% (v/v) glycerol, pH: 8
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2019 May 1
Structural Analysis of Pathogenic Mutations Targeting Glu427 of ALDH7A1, the Hot Spot Residue of Pyridoxine-Dependent Epilepsy. J Inherit Metab Dis (2019)
Laciak AR, Korasick DA, Gates KS, Tanner JJ
RgGuinier 3.7 nm
Dmax 11.3 nm
VolumePorod 256 nm3

SASDGQ4 – Human alpha-aminoadipic semialdehyde dehydrogenase (ALDH)7A1 E399D at 2.9 mg/mL

UniProt ID: P49419 (None-None) Alpha-aminoadipic semialdehyde dehydrogenase
Alpha-aminoadipic semialdehyde dehydrogenase experimental SAS data
PDB (PROTEIN DATA BANK) model
Sample: Alpha-aminoadipic semialdehyde dehydrogenase, 56 kDa Homo sapiens protein
Buffer: 50 mM HEPES, 100 mM NaCl, 1 mM DTT, 10 mM NAD, 2% (v/v) glycerol, pH: 8
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2019 May 1
Structural Analysis of Pathogenic Mutations Targeting Glu427 of ALDH7A1, the Hot Spot Residue of Pyridoxine-Dependent Epilepsy. J Inherit Metab Dis (2019)
Laciak AR, Korasick DA, Gates KS, Tanner JJ
RgGuinier 3.8 nm
Dmax 11.4 nm
VolumePorod 260 nm3

SASDGR4 – Human alpha-aminoadipic semialdehyde dehydrogenase (ALDH)7A1 E399D at 5.7 mg/mL

UniProt ID: P49419 (None-None) Alpha-aminoadipic semialdehyde dehydrogenase E399D
Alpha-aminoadipic semialdehyde dehydrogenase E399D experimental SAS data
PDB (PROTEIN DATA BANK) model
Sample: Alpha-aminoadipic semialdehyde dehydrogenase E399D, 56 kDa Homo sapiens protein
Buffer: 50 mM HEPES, 100 mM NaCl, 1 mM DTT, 10 mM NAD, 2% (v/v) glycerol, pH: 8
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2019 May 1
Structural Analysis of Pathogenic Mutations Targeting Glu427 of ALDH7A1, the Hot Spot Residue of Pyridoxine-Dependent Epilepsy. J Inherit Metab Dis (2019)
Laciak AR, Korasick DA, Gates KS, Tanner JJ
RgGuinier 3.9 nm
Dmax 10.6 nm
VolumePorod 272 nm3

SASDGS4 – Human alpha-aminoadipic semialdehyde dehydrogenase (ALDH)7A1 E399G at 1.6 mg/mL

UniProt ID: P49419 (None-None) Alpha-aminoadipic semialdehyde dehydrogenase E399G
Alpha-aminoadipic semialdehyde dehydrogenase E399G experimental SAS data
PDB (PROTEIN DATA BANK) model
Sample: Alpha-aminoadipic semialdehyde dehydrogenase E399G, 55 kDa Homo sapiens protein
Buffer: 50 mM HEPES, 100 mM NaCl, 1 mM DTT, 10 mM NAD, 2% (v/v) glycerol, pH: 8
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2019 May 1
Structural Analysis of Pathogenic Mutations Targeting Glu427 of ALDH7A1, the Hot Spot Residue of Pyridoxine-Dependent Epilepsy. J Inherit Metab Dis (2019)
Laciak AR, Korasick DA, Gates KS, Tanner JJ
RgGuinier 3.8 nm
Dmax 11.3 nm
VolumePorod 290 nm3

SASDGT4 – Human alpha-aminoadipic semialdehyde dehydrogenase (ALDH)7A1 E399G at 3.2 mg/mL

UniProt ID: P49419 (None-None) Alpha-aminoadipic semialdehyde dehydrogenase E399G
Alpha-aminoadipic semialdehyde dehydrogenase E399G experimental SAS data
PDB (PROTEIN DATA BANK) model
Sample: Alpha-aminoadipic semialdehyde dehydrogenase E399G, 55 kDa Homo sapiens protein
Buffer: 50 mM HEPES, 100 mM NaCl, 1 mM DTT, 10 mM NAD, 2% (v/v) glycerol, pH: 8
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2019 May 1
Structural Analysis of Pathogenic Mutations Targeting Glu427 of ALDH7A1, the Hot Spot Residue of Pyridoxine-Dependent Epilepsy. J Inherit Metab Dis (2019)
Laciak AR, Korasick DA, Gates KS, Tanner JJ
RgGuinier 3.7 nm
Dmax 10.6 nm
VolumePorod 250 nm3

SASDGU4 – Human alpha-aminoadipic semialdehyde dehydrogenase (ALDH)7A1 E399G at 6.5 mg/mL

UniProt ID: P49419 (None-None) Alpha-aminoadipic semialdehyde dehydrogenase E399G
Alpha-aminoadipic semialdehyde dehydrogenase E399G experimental SAS data
PDB (PROTEIN DATA BANK) model
Sample: Alpha-aminoadipic semialdehyde dehydrogenase E399G, 55 kDa Homo sapiens protein
Buffer: 50 mM HEPES, 100 mM NaCl, 1 mM DTT, 10 mM NAD, 2% (v/v) glycerol, pH: 8
Experiment: SAXS data collected at 12.3.1 (SIBYLS), Advanced Light Source (ALS) on 2019 May 1
Structural Analysis of Pathogenic Mutations Targeting Glu427 of ALDH7A1, the Hot Spot Residue of Pyridoxine-Dependent Epilepsy. J Inherit Metab Dis (2019)
Laciak AR, Korasick DA, Gates KS, Tanner JJ
RgGuinier 3.8 nm
Dmax 10.0 nm
VolumePorod 270 nm3