SASBDB entries for UniProt ID: Q14896

SASDB25 – Cardiac myosin binding protein-C: domains C5-C6-C7

UniProt ID: Q14896 (641-964) Cardiac myosin binding protein-C: domains C5-C6-C7
Cardiac myosin binding protein-C: domains C5-C6-C7 experimental SAS data
Cardiac myosin binding protein-C: domains C5-C6-C7 Kratky plot
Sample: Cardiac myosin binding protein-C: domains C5-C6-C7 monomer, 36 kDa Homo sapiens protein
Buffer: 25 mM Tris-HCl, 250 mM NaCl, 2 mM TCEP, 0.02% sodium azide, pH: 7.5
Experiment: SAXS data collected at SAXS/WAXS, Australian Synchrotron on 2015 Apr 18
Clinically Linked Mutations in the Central Domains of Cardiac Myosin-Binding Protein C with Distinct Phenotypes Show Differential Structural Effects. Structure 24(1):105-115 (2016)
Nadvi NA, Michie KA, Kwan AH, Guss JM, Trewhella J
RgGuinier 3.8 nm
Dmax 14.1 nm
VolumePorod 55 nm3

SASDDD9 – Cardiac myosin binding protein C: tri-helix bundle from the motif with C2 domain

UniProt ID: Q14896 (319-451) cardiac myosin binding protein C: tri-helix bundle-C2
cardiac myosin binding protein C: tri-helix bundle-C2 experimental SAS data
Cardiac myosin binding protein C: tri-helix bundle from the motif with C2 domain Rg histogram
Sample: Cardiac myosin binding protein C: tri-helix bundle-C2 monomer, 15 kDa human sequence obtained … protein
Buffer: 150 mM NaCl, 10 mM MES, 2 mM TCEP, 1 mM NaN3 at 4°C, pH: 6.5
Experiment: SAXS data collected at SAXS/WAXS, Australian Synchrotron on 2015 Apr 18
A Highly Conserved Yet Flexible Linker Is Part of a Polymorphic Protein-Binding Domain in Myosin-Binding Protein C. Structure 24(11):2000-2007 (2016)
Michie KA, Kwan AH, Tung CS, Guss JM, Trewhella J
RgGuinier 1.9 nm
Dmax 8.0 nm
VolumePorod 20 nm3